5-lipoxygenase inhibitor具有抑制5-脂肪氧合酶作用的式I新化合物及其可药用盐,其中Ar The novel compounds I and their pharmaceutically acceptable salts have 5-lipoxygenase inhibitory action of the formula, wherein Ar罗德尼·W·史蒂文斯真野高司中尾一成奥村祥征...
[2]The natural dual cyclooxygenase and 5-lipoxygenase inhibitor flavocoxid is protective in EAE through effects on Th1/Th17 differentiation and macrophage/microglia activation[J].Weimin Kong,Kirsten M.Hooper,Doina Ganea.Brain Behavior and Immunity.2015 [3]Phosphorylation of serine 523 on 5-lipoxygenas...
英文名称 Anti-5 lipoxygenase中文名称 5-脂氧合酶抗体浓度1mg/1ml 规格0.1ml/100μg 0.2ml/200μg抗体来源 Rabbit 克隆类型 polyclonal 交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit产品类型 一抗 连续使用时4°C存储,保质期六个月,长期存储时建议分装为10ul以上小包装-20°C存储,并避免...
Zileuton是一种5-脂氧合酶抑制剂(5-lipoxygenase抑制剂),阻断环氧合酶诱导的脂质过氧化,是一种铁死亡抑制剂(Ferroptosis抑制剂)。 产品信息 货号 54036ES25 规格 25 mg 价格 485 产品性质 英文别名(English Synonym) A-64077; A64077; A 64077; Abbott 64077; Abbott64077; ZYFLO ...
This invention relates to novel AKBA analogs of the formula I given below: Where in R1, R2, R3, R4 and R5 in each of the said analogs are: 1. R1═OCHO, R2═H, R3═COOH, R4 & R5═O 2. R1═OCOCH2Cl, R2═H, R3═COOH, R4 & R5═O 3. R1═5′-O-methylgalloyloxy
囹论著囹基础研究夺·1473·5一脂氧合酶抑制剂齐留通抑制二乙基亚硝胺诱导大鼠肝细胞癌形成的实验研究邓君健,徐细明,郭红庭,向淼,吴耀贵,戈伟,张一桥Zileuton,a5一lipoxygenasespecificinhibitordielhyInitr0SamIneinratsanditsmechanismpreventshepaf0CarCin0geneSiSinducedbyDENGJunjian,XUXiming,GUOHonking,XIANGMiao,WUYao...
Zileuton是一种有效的,选择性的5-lipoxygenase抑制剂,具有抗炎的作用。注:本品仅可用于科研实验,严禁用于临床医疗及其他用途!CAS号:111406-87-2别名:A 64077;Abbott 64077纯度:99.84%分子式:C11H12N2O2S分子量:236.29结构式:储存条件:-20℃,有效期2年,溶入溶剂后-20℃请尽量在一个月内使用。相关搜索:5-...
5-LOx-in-2 is a 5-lipoxygenase inhibitor (5-LOX) with an IC50 value of 0.33 μM. 5-lox-in-2 inhibits 5-LOX action IN a dose-dependent manner. 5-LOX-IN-2 can reduce the cell activity of kidney cancer cells and induce apoptosis, and can be used in cancer research. 靶点活性 5-...
关键词:5一脂氧舍酶;肿瘤;增殖;凋亡 中围分类号:R730.23;Q554文献标识码:A 文章编号2003】0l一0057—04 5一脂氧合酶(5-lipoxygenase,5LO)是催化花生四对发现抗癌新靶点、研制抗癌新药具有重要意义。 烯酸(arachidonicacid,AA)转化为白三烯(LT)和氢氧 1花生四烯酸的5-脂氯台酶代谢通路 化物5HETE的关键酶...
LT biosynthesis is initiated by 5-lipoxygenase (5-LOX) with the assistance of the substrate-binding 5-LOX-activating protein at the nuclear membrane. Here, we contrast the structural and functional consequences of the binding of two natural product inhibitors of 5-LOX. The redox-type inhibitor ...