A 5-formyltetrahydrofolate cycloligase paralog from all domains of 754 life: comparative genomic and experimental evidence for a cryptic role in 755 thiamin metabolism. Funct. Integr. Genomics 11, 467-478. 756 doi:10.1007/s10142-011-0224-5. 757 Pringault, O., and Garcia-Pichel, F. (2004...
5-Formyltetrahydrofolate (5-CHO-THF) is formed via a second catalytic activity of serine hydroxymethyltransferase (SHMT) and strongly inhibits SHMT and other folate-dependent enzymes in vitro. The only enzyme known to metabolize 5-CHO-THF is 5-CHO-THF cycloligase (5-FCL), which catalyzes its...
5-NH=CH-THF 5-formiminotetrahydrofolate 5-FCL 5-formyltetrahydrofolate cycloligase FIGLU N-formimino-l-glutamate FT glutamate formiminotransferase FT-CD glutamate formiminotransferase-cyclodeaminase IPTG isopropyl-β-d-thiogalactopyranoside SHMT serine hydroxymethyltransferase. ...
A 5-formyltetrahydrofolate cycloligase paralog from all domains of 754 life: comparative genomic and experimental evidence for a cryptic role in 755 thiamin metabolism. Funct. Integr. Genomics 11, 467-478. 756 doi:10.1007/s10142-011-0224-5. 757 Pringault, O., and Garcia-Pichel, F. (2004...
A 5-formyltetrahydrofolate cycloligase paralog from all domains of 754 life: comparative genomic and experimental evidence for a cryptic role in 755 thiamin metabolism. Funct. Integr. Genomics 11, 467-478. 756 doi:10.1007/s10142-011-0224-5. 757 Pringault, O., and Garcia-Pichel, F. (2004...