5-fluorouridine 5'-triphosphate 英文别名: 5-Fluoro-UTP;Uridine 5'-(tetrahydrogen triphosphate), 5-fluoro- 中文名: 中文别名: CBNumber: CB71388036 分子式: C9H14FN2O15P3 分子量: 502.13 MOL File: 3828-96-4.mol 化学性质安全信息用途供应商7 ...
5-Fluorouridine 5-triphosphate, tetraammonium salt 英文别名: 5-Fluorouridine 5-triphosphate, tetraammonium salt 中文名: 中文别名: CBNumber: CB15418355 分子式: C9H27FN6O16P3 分子量: 587.2609662 MOL File: Mol file 化学性质安全信息用途供应商1 ...
CAS号:1630828-71-5 英文名:2'-Deoxy-5-fluorouridine-5'-triphosphate sodium salt 中文名: CBNumber:CB98397859 分子式:C9H15FN2NaO14P3 分子量:510.13 MOL File:1630828-71-5.mol2'-Deoxy-5-fluorouridine-5'-triphosphate sodium salt上下游产品信息...
5-fluorouridine 5′-triphosphatecapecitabinehand-and-foot syndromeMarkov modellingpopulation pharmacokineticsCapecitabine is an oral pro-drug of 5-fluorouracil. Patients with solid tumours who are treated with capecitabine may develop hand-and-foot syndrome (HFS) as side effect. This might be a result...
Following exposure to tumor cells, all four fluoropyrimidines were metabolized to identical products (i.e., FUra, 5-fluorouridine 5'-monophosphate, 5-fluorouridine 5'-diphosphate, 5-fluorouridine 5'-triphosphate, and 5-fluoro-2'-deoxyuridine 5'-monophosphate), all produced an incorporation of ...
The phosphorylation of 5'-deoxy-5-fluorouridine (doxifluridine, 5'-DFUR) has been achieved using inorganic cyclo-triphosphate (P(3m), Na(3)P(3)O(9)) and monoimido-cyclo-triphosphate (MCTP, Na(3)P(3)O(8)NH) in aqueous solution. In the reaction of 5'-DFUR with P(3m), 2'-mono...
(2-methoxyethyl)-5-methyluridine | 3’,5’-Di-O-benzoyl-2’-deoxy-2’-fluoro-5-methyl-β-D-arabino-uridine | 2’-Deoxy-2’-fluoro-4-thio-beta-D-arabinouridine | 2’-Deoxy-2’-fluoro-N3-[(pyrid-2-yl)methyl]-beta-D-arabinouridine | Uridine triphosphate-13C9,15N2 sodium | 2'-...
英文同义词: 2'-deoxy-5-[3-[[(2',7'-difluoro-3',6'-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-5-yl)carbonyl]amino]-1-propenyl]uridine Uridine 5′-(tetrahydrogen triphosphate), 2′-deoxy-5-[3-[[(2′,7′-difluoro-3′,6′-dihydroxy-3-oxospiro[isobenzofuran-...
5'-Deoxy-5-fluorouridine (dFUrd) needs intracellular activation via 5-fluorouracil into 5-fluoro-2'-deoxyuridine-5'-monophosphate and 5-fluorouridine-S'-triphosphate. In the present study, the cytotoxic activity of dFUrd in vitro and dFUrd combined with daunorubicin (DNR) was assessed with ...
In L1210 cells, FU was anabolized to 5-fluorouridine triphosphate and 5-fluorodeoxyuridine monophosphate, whereas dFUR was present mainly as the unchanged drug. Further metabolism studies using dFUR with tritium label in either the FU moiety or the altered sugar moiety established that the ...