化学名 5-FLUOROURIDINE MONOPHOSPHATE 分子式 C9H12FN2O9P CAS号 796-66-7 结构式图片 SMILES O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(O)=O)N2C=C(F)C(=O)NC2=O INCHIKEY RNBMPPYRHNWTMA-UAKXSSHOSA-N 别名 5-FLUOROURIDYLIC ACID;5-FLUOROURIDINE 5'-MONOPHOSPHATE;5'-...
英文名称: 5-FLUOROURIDINE 5'-MONOPHOSPHATE, DIAMMONIUM SALT 英文同义词: 5-FLUOROURIDINE 5'-MONOPHOSPHATE, DIAMMONIUM SALT CAS号: 分子式: C9H18FN4O9P 分子量: 376.23 EINECS号: Mol文件: Mol File 5-FLUOROURIDINE 5'-MONOPHOSPHATE, DIAMMONIUM SALT 信息错误报告 提交 按省份浏览5-FLUOROURIDINE ...
Journal of Fermentation and BioengineeringFujita, K.-I., Hisada, Y., Matsukawa, A., Shibata, K., Tanaka, T., Taniguchi, M., and Oi, S.: Microbial synthesis of 5-fluorouridine monophosphate and 5-fluoro-2'-deoxyuri- dine monophosphate. J. Ferment. Bioeng., 77, 696-699 (1994)....
5'-[4-(Pivaloyloxy)-1,3,2-dioxaphosphorinan-2-yl]-2'-deoxy-5 -fluorouridine (1c) was designed as a potential membrane-permeable prodrug of 2'-deoxy-5-fluorouridine 5'-monophosphate (FdUMP), a putative active metabolite of the antitumor d... D Farquhar,R Chen,S Khan - 《Journal ...
Following exposure to tumor cells, all four fluoropyrimidines were metabolized to identical products (i.e., FUra, 5-fluorouridine 5'-monophosphate, 5-fluorouridine 5'-diphosphate, 5-fluorouridine 5'-triphosphate, and 5-fluoro-2'-deoxyuridine 5'-monophosphate), all produced an incorporation of ...
Fluorodeoxyuridylate;5-fluoro-2'-deoxyuridine-5'-O-monophosphate;2’-Deoxy-5-Fluorouridine 5’-phosphate triethyl ammonium salt中文名: 化合物 2'-DEOXY-5-FLUOROURIDINE 5'-PHOSPHATE TRIETHYL AMMONIUM SALT中文别名: 化合物 2'-DEOXY-5-FLUOROURIDINE 5'-PHOSPHATE TRIETHYL AMMONIUM SALTCBNumber...
3′-fluoro 2′,3′-dideoxynucleoside analogs for in vitro antiviral activity studies. 3′-fluoro deoxyuridine monophosphate analogs as potential anti parasites. 关联靶点 名称和识别符 化学和物理性质 安全和危险性(GHS) 质检证书(COA) 相关文档 溶液计算器...
This may be exemplified by the blockade of thymidylate synthase (EC 2.1.1.45) by 5-f luorodeoxyuridine 5'-monophosphate, a metabolite of the pyrimidine analogs 5-fluorouracil, 5-f luorodeoxyuridine, or 5-fluorouridine (1). Inhibition of thymidylate synthase can lead to a depletion of thymine...
In L1210 cells, FU was anabolized to 5-fluorouridine triphosphate and 5-fluorodeoxyuridine monophosphate, whereas dFUR was present mainly as the unchanged drug. Further metabolism studies using dFUR with tritium label in either the FU moiety or the altered sugar moiety established that the ...
5'-Deoxy-5-fluorouridine (dFUrd) needs intracellular activation via 5-fluorouracil into 5-fluoro-2'-deoxyuridine-5'-monophosphate and 5-fluorouridine-5'-triphosphate. In the present study, the cytotoxic activity of dFUrd in vitro and dFUrd combined with daunorubicin (DNR) was assessed with ...