5.UTR（Untranslated Regions）：即非翻译区，是信使RNA（mRNA）分子两端的非编码片段。5'-UTR从mRNA起...
1. 基因经过转录形成Pre mRNA,这里面包含着内含子和外显子(5端是以外显子打头,但是这段外显子不仅包含CDS,还包含5' UTR;3端是以外显子结束,但是这段外显子不仅包含CDS,还包含3' UTR),经过剪接形成成熟mRNA,内含子已减掉,如果抛开后来加上去的cap和poly A的话,这时全是外显子,但是不全是CDS,因为只有中...
5' UTR,3' UTR 叫作 untranslated region ,而 introns 叫作non-coding RNA。一段基因序列上包含外显子和内含子,转录的时候,pre-RNA就是前体RAN上会有内含子和外显子,成为成熟RNA时,内含子已经被剪切了,只保留外显子,所以内含子叫作非编码RNA(non-coding RNA)。但成熟的RNA上也是有一部分序列并不翻译成蛋白...
Each gene MODEL can encode several mRNA EXONS and represent the spliced, intronless portions of the gene. An mRNA EXON may only partially code for a protein; exactly the case where upstream or downstream untranslated regions exist. The protein coding portion of an individual EXON is represented ...
Each gene MODEL can encode several mRNA EXONS and represent the spliced, intronless portions of the gene. An mRNA EXON may only partially code for a protein; exactly the case where upstream or downstream untranslated regions exist. The protein coding portion of an individual EXON is represented ...
At least six different 5′-UTR exons (UTRs 1–6) were detected in NRF-1 transcripts. These exons were mapped to human NRF-1 genomic clones and their sequences, including donor and acceptor splice junctions, determined. Two of the human UTR exons were derived from insertions of Alu-sq ...
一、5‘UTR，是从5'帽到起始密码子（不含）二、CDS，从起始密码子（含）到终止密码子（不含终止子...
Here using the MANE v1.0 cDNA sequences, a set of all possible single nucleotide variants, and small indels (up to 3 bp in length) were generated within 5’ UTR exons. We then annotated these variants with their variant effect using the Ensembl Variant Effect Predictor Version 103 with the...
We have identified two novel exons of the NOD2 gene (designated exon 1a and 1b), which are spliced to the canonical exon 2 and constitute the 5' untranslated region of two alternative transcript isoforms (i.e. exon 1a/1b/2 and exon 1a/2). The two novel transcripts are abundantly expr...
Thus, genes with long 5UIs tend to have a high total intronic length and longer 5'UTR exons. While this tendency holds in genes with additional introns, several genes with total 5UI lengths greater than 10 kb lack any coding-region or 3'UTR introns (Figure 1d). On the other hand, amo...