EXAMPLE:5-Deoxy-5-difluoromethylthio-D-ribose. USE:A remedy for tumor having excellent antitumor activity and low toxicity. PREPARATION:The objective compound can be produced e.g. by (1) using methyl 2,3-O-isopropylidene-5-O-(p-toluenesufonyl)-D-ribofranoside of formula II as a ...
5-Deoxy-5-(methylthio)ribose 物化性质 实验特性 LogP-1.36900 PSA69.92 折射率1.605 沸点358°Cat760mmHg 闪点170.3°C 密度1.474 计算特性 精确分子量180.04566 氢键供体数量3 氢键受体数量5 可旋转化学键数量5 同位素质量180.04563 重原子数量11 复杂度119 ...
英文名 5-methylthioribose kinase 英文别名 5-methylthioribose kinase 您刚刚浏览过 5-methylthioribose kinase 刚刚更新的化工产品 65989-27-7 66003-73-4 66003-69-8 65989-13-1 66941-42-2 651307-63-0 65988-97-8 66003-64-3 651307-59-4 66003-61-0 66941-41-1 651307-58-3 65987-47-5 ...
The presence of a previously unidentified enzyme, tentatively designated 5-methylthioribose kinase, has been demonstrated in cell-free extracts of Enterobacter aerogenes. The enzyme catalyzes the ATP-dependent phosphorylation of 5-methylthioribose. ADP is one of the products of the reaction and, based...
5-methylthioribose 1-phosphate APH(3')-IIIa: 3',5"-aminogylcoside phosphotransferase type IIIa cAMP: cyclic adenosine monophosphate PKA: protein kinase A RMSD: root mean square deviation ATPγS: adenosine 5'-(β,γ-thio)triphosphate FAD: flavin adenine dinucleotide NAD(P)H: nicotin...
(Supplementary Fig.5and Table1), analogous toB. subtilis5-methylthioribose kinase21and other kinases22. The specificity constant for DrdI with dR1P as substrate (Table1) was comparable to that of a bacterial D-ribose isomerase23but substantially lower than that ofB. subtilis5-methylthioribose 1-...
shapeindiceswereimportanttotheactivityof inhibitors. Keywords:MTA;multi—linearregression(MLR);QSAR;moleculardescriptors O 引言 5一甲硫腺苷核苷酶(5'-methylthioadenosine nucleosidase,MTAN,EC3.2.2.16)专一性催化 底物 5一甲硫腺苷(5'-methylthioadenosine, MTA)生成5一甲硫核糖(5一methylthioribose, MTR)和腺...
Crystal structure of 5-methylthioribose 1-phosphate isomerase product complex from Bacillus subtilis: Implications for catalytic mechanism Crystal structure of 5-methylthioribose 1-phosphate isomerase product complex from Bacillus subtilis: implications for catalytic mechanism. Protein Sci - Tamura... Haruka...
Affinity purification of 5-methylthioribose kinase and 5-methylthioadenosine/S-adenosylhomocysteine nucleosidase from Klebsiella pneumoniae [corrected]: Two enz
5′-methylthioadenosineMeS-Rib-1-P5′-methylthioribose-1-phosphateMeS-RibmethylthioriboseRib-1-Pribose-1-phosphateAdoMetadenosylmethionineThe kinetics of ... MJ Snare,PJ Thistlethwaite,KP Ghiggino - 《Journal of the American Chemical Society》 被引量: 182发表: 1983年 Review article: maintenance of...