NSC 26480(5,6-二氢-5-氮胞苷) CAS号: 62402-31-7 英文名: NSC 26480 (5,6-dihydro-5-azacytidine) 英文别名: NSC 26480 (5,6-dihydro-5-azacytidine);6-Amino-3-((2r,3r,4s,5r)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3,4-dihydro-1,3,5-triazin-2(1h)-one hydrochloride...
5,6-二氢-5-氮杂胞苷化学性质 熔点: 216-221 °C (decomp) 密度: 2.10±0.1 g/cm3(Predicted) 酸度系数(pKa): 9.75±0.20(Predicted) EPA化学物质信息: 5,6-Dihydro-5-azacytidine (62488-57-7) 安全信息 5,6-二氢-5-氮杂胞苷性质、用途与生产工艺 ...
5,6-DIHYDRO-5-AZACYTIDINE,来源于药化词典-药智数据
A major disadvantage of 5-azacytidine and 5-aza-2′-deoxycytidine is their instability in neutral aqueous solution. This resulted in the development of more stable cytidine analogs, such as 5,6-dihydro-5-azacytidine and 5-fluoro-2′-deoxycytidine [61]. 5,6-Dihydro-5-azacytidine has received ...
Dihydro-5-azacytidine (DHAC) is a hydrolytically stable congener of 5-azacytidine, which retains antileukemic activity against experimental leukemias. The biochemical pharmacology of DHAC was studied in tumor-bearing mice in order to elucidate the mode of action of this drug. We found that after ...
Dihydro-5-azacytidine (DHAC) 是一种核苷类似物,可掺入 DNA 并抑制 DNA 甲基化 (DNA methylation)。Dihydro-5-azacytidine 具有抗肿瘤活性。 Dihydro-5-azacytidineChemical Structure CAS No. :62488-57-7 *Please selectQuantitybefore adding items.
6-AZACYTIDINE CAS No: 3131-60-0 5,6-dihydro-5-azacytidine CAS No: 62488-57-7 5'-azacytidine 5'-monophosphate CAS No: 2226-72-4 6-AMino-5-azacytidine CAS No: 105331-00-8 2'',3'',5''-Triacetyl -azacytidine CAS No: 10302-78-0 TRI-O-BENZOYL-D-GALACTAL CAS No: 34948-...
DNA methyltransferase 1 is an enzyme encoded by DNMT1 gene that catalyzesDNA methylation, a process where inmethyl groupsare transferred to specificCpG islandsof DNA [26]. DNA methylation is an important step in epigenetic regulation [27]. Thedeoxycytidine triphosphateanalogues of 5-azacytidine andde...
The effect of 5-azacytidine (AZC) and 5,6-dihydro-5-azacytidine (DHAZC) on nRNA synthesis was studied in L1210 cells in vitro. AZC produced 50% inhibition of the incorporation of [14C]uridine into nuclear rRNA and nonpolyadenylic acid an... RI Glazer,AL Peale,JA Beisler,... - 《...
Azacytidine Azacytidine, 5- L-β-Ribofuranosyl-5-azacytosine ladakamycin[Wiki] MFCD00006539[MDL number] Unverified 1-[(4S,2R,3R,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-amino-1,3,5-tri azin-2-one 1-[(4S,2R,3R,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-...