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英文别名4-OHT | SR-01000759243 | 4-((1Z)-1-(4-(2-(dimethylamino)ethoxy)phenyl)-2-phenyl-1-butenyl)phenol | 4-OH-TAM | CAS-68047-06-3 | 17197F0KYM | A904472 | BIDD:PXR0104 | Opera_ID_600 | Hydroxytamoxifen | Q4689254 | TAMOXIFEN, 4-HYDROXY-, (Z)- | (Z)-4-OHT | HB6...
Microsphere-encapsulated 4OH-Tamoxifen: a new sustained release delivery system with antitumour activity against DMBA-induced mammary carcinoma in sprague-dawley ratsConclusions✓ A significant antitumor activity was displayed by TAM and MS/4OH-TAM✓ A single SC injection of MS/4OH-TAM displayed ...
4-Hydroxytamoxifen是tamoxifen的活性代谢产物,是一种选择性的雌激素受体调节分子,在乳腺癌的治疗和化学疗法中应用广泛化疗药物它莫西芬的代谢产物,抑制许多潜在雌激素的活性,也能激活如膜间脂质过氧化反应的抑制剂。 4-hydroxytamoxifen (OHT), an active metabolite of tamoxifen, is a selective estrogen receptor mo...
As tamoxifen sensitivity depends on the estrogen receptor (ERα) expression level, we evaluated the effect of PUGNAc+glucosamine on the expression of this receptor. We observed that O-GlcNAcylation-inducing treatment significantly reduced the expression of ERα mRNA and protein, suggesting a potential...
Potent inhibition of rhabdoid tumor cells by combination of flavopiridol and 4OH-tamoxifen. BMC Cancer 10, 634 (2010).Cimica V, Smith ME, Zhang Z, Mathur D, Mani S, Kalpana GV. Potent inhibition of rhabdoid tumor cells by combination of flavopiridol and 4OH-tamoxifen. BMC Cancer. 2010 ...
Regulation of sialyltransferase expression by estradiol and 4-OH-tamoxifen in the human breast cancer cell MCF-7. Mol Cell Biol Res Commun 2000;3:48-52.Peyrat, J. P., Recchi, M. A., Hebbar, M., Pawlowski, V., Hornez, L., Le Bourhis, X., Hondermarck, H., Harduin-Lepers, A.,...
Update on percutaneous 4-OH tamoxifen4-hydroxy tamoxifène, Marqueurs de prolifération, CCIS, 4-hydroxy-tamoxifen, Proliferative markers, DCISPhilippe Rouanet
Coopman P, Garcia M, Brunner N, Derocq D, Clarke R, Rochefort H 1994 Anti-proliferative and anti-estrogenic effects of ICI 164,384 and ICI 182,780 in 4-OH-tamoxifen-resistant human breast-cancer cells. Int J Cancer 56:295-300
DIFFERENCE IN BIOLOGICAL CHARACTER OF ENDOXIFEN, 4-OH TAMOXIFEN, TOREMIFENE AND FULVESTRANT FOR MCF-7 CELLPaclitaxel (TXL) and docetaxel (TXT), especially TXL, cause neurotoxicity manifested as polyneuropathy. In clinical practice, detailed knowledge of the symptoms and effect on quality of life (...