4EGI-1产品是4EGI-1 is an inhibitor of the interaction of translation initiation factor eIF4G to eIF4E. It inhibits the binding of eIF4G to eIF4E, but not 4E-BP1. The KD for eIF4E binding to 4EGI-1 is 25 μM ± 11 μM. It inhibits proliferation of human cancer cells. It reduces...
4EGI-1 (eIF4E/eIF4G interaction inhibitor)4EGI-1 (see Fig. E9 ) inhibits complex formation between translation initiation factors eIF4E and eIF4G (Moerke NJ et al 2007 Cell 128:257). Figure E9.doi:10.1007/978-1-4020-6754-9_5129Springer NetherlandsSpringer Netherlands...
4EGI-1 是一种竞争性 eIF4E/eIF4 g 相互作用抑制剂,与 eIF4E 结合,Kd 值为 25 μM。 规格价格库存数量 1 mg¥ 313现货 2 mg¥ 445现货 5 mg¥ 795现货 10 mg¥ 995现货 25 mg¥ 1,990现货 50 mg¥ 2,890现货 1 mL x 10 mM (in DMSO)¥ 866现货 ...
已经表明,尽管4EGI-1从eIF4E置换出eIF4G,但其却同时增强了体内和体外的4E-BP缔合。4E-BPs调节了eIF4E / eIF4G复合体,该复合体在翻译起始水平上对基因表达的调控中起着核 eIF4E/eIF4G Interaction Inhibitor, 4EGI-1, has been shown to amplify TRAIL (tumor necrosis factor-related apoptosis-inducing ligand)...
eIF4E与eIF4G相互作用抑制剂(4EGI-1) 英文名称: 4EGI-1 产品规格: 1mL(10mM)|5mg|10mg|25mg|50mg|100mg 发货周期: 1～3天 产品价格: 询价 4EGI-1抑制eIF4E与eIF4G相互作用,作用于HNE1细胞72小时IC50值为50μM。注:本品仅可用于科研实验,严禁用于临床医疗及其他用途!CAS号:315706-13-9纯度:98.0%分...
4egi-1, a competitive eif4e/eif4 g interaction inhibitor, binds to eif4e(kd=25 μm). 价格:￥电议型 号:T2665产 地:中国大陆 T26654EGI-1;化合物4EGI-14EGI 1;4EGI 1 4egi-1, a competitive eif4e/eif4 g interaction inhibitor, binds to eif4e(kd=25 μm). ...
4EGI-1 is a competitiveeIF4E/eIF4Ginteraction inhibitor by binding to eIF4E withKDof 25 μM. 4EGI-1 specifically inhibits the function ofmTORby blocking the activation of4E-BP1. 4EGI-1 inducesapoptosis. 4EGI-1 Chemical Structure CAS No. 315706-13-9 ...
化学数据 CAS号315706-13-9货号BCP28021 中文名4EGI-1 英文名4EGI-1 中文别名 英文别名4EGI1; 4EGI1; 4 EGI1; 4-EGI1; 4 EGI 1; 4-EGI-1; 分子式C18H12Cl2N4O4S分子量451.28 本页面部分数据来自于公开的网络资源,所以瀚香生物不能保证其准确性。
4EGI-1结构式 常用名 4EGI-1 英文名 eIF4E/eIF4G Interaction Inhibitor, 4EGI-1 CAS号 315706-13-9 分子量 451.28 密度 1.6±0.1 g/cm3 沸点 712.2±70.0 °C at 760 mmHg 分子式 C18H12Cl2N4O4S 熔点 N/A MSDS N/A 闪点 384.5±35.7 °C ...
The pan-caspase inhibitor significantly reduced the 4EGI-1 induced apoptosis (50% inhibition), the caspase-9 inhibitor was as potent as the pan-caspase inhibitor showing the involvement of the intrinsic pathway (Figure 2C). To confirm the importance of this pathway, Bax activation was determined...