4-1BB signaling beyond T cells. Cell Mol Immunol. 2011;8:281–4. CentralVinay, D.S. and B.S. Kwon, 4-1BB signaling beyond T cells. Cell Mol Immunol, 2011. 8(4): p. 281-4.Dass S Vinay,Byoung S Kwon. 4-1BB signaling beyond T cells[J]. 2011.doi:10.1038/cmi.2010.82...
参考：https://www.jbc.org/article/S0021-9258%2820%2933839-4/fulltexthttps://www.creative-diagnostics.com/4-1bb-4-1bbl-signaling-pathway.htmhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226203/https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8919572/ ...
https://www.jbc.org/article/S0021-9258%2820%2933839-4/fulltext https://www.creative-diagnostics.com/4-1bb-4-1bbl-signaling-pathway.htm https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226203/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8919572/ 联系我们 吉满生物助力药物研发,紧随前沿靶点...
[1] Guo, G., Gong, K., Wohlfeld, B., Hatanpaa, K. J., Zhao, D., and Habib, A. A. (2015). Ligand-independent EGFR signaling. Cancer Res.75, 3436–3441. [2] Croft M. The role of TNF superfami...
Vinay DS, Kwon BS. 4-1BB signaling beyond T cells. Cell Mol Immunol. 2011 Jul;8(4):281-4. Bartkowiak T, Curran MA. 4-1BB Agonists: Multi-Potent Potentiators of Tumor Immunity. Front Oncol. 2015 Jun 8;5:117. Chester C, Sanmamed MF, Wang J, Melero I. Immunotherapy targeting 4-...
2024年6月18日,意大利IRCCS圣拉斐尔科学研究所的研究人员在国际顶尖学术期刊Cell上发表了题为:Therapeutic potential of co-signaling receptor modulation in hepatitis B的研究论文。 该研究探索了功能失调的HBV特异性CD8+T细胞的行为和潜在的...
1.Pichler, A.C., et al., TCR-independent CD137 (4-1BB) signaling promotes CD8+-exhausted T cell proliferation and terminal differentiation. Immunity, 2023. 56(7): p. 1631-1648.e10. 关于礼进生物 礼进生物是一家领先的生物科技医药公司,专注于开发创新的肿瘤免疫新药和疗法。礼进生物利用其自主...
5.Benjamin I Philipson et al,4-1BB costimulation promotes CAR T cell survival through noncanonical NF-κB signaling,Sci Signal . 2020 Mar 31;13(625):eaay8248. 6.Chester C, Sanmamed MF, Wang J, Melero I.Immunotherapy targeting 4-1BB: mechanistic rationale, clinical results, and future ...
Overall, the present study suggests that since 4-1BB signaling is dependent upon CD28 signaling, combined blo- ckage of the two costimulatory molecules may not be an effective way to induce tolerance to allografts. The dependency of 4-1BB signals on the CD28 costimulatory pathway implies that ...
Vinay DS, Kwon BS. 4-1BB signaling beyond T cells. Cell Mol Immunol. 2011 Jul;8(4):281-4. Bartkowiak T, Curran MA. 4-1BB Agonists: Multi-Potent Potentiators of Tumor Immunity. Front Oncol. 2015 Jun 8;5:117. Chester C, Sanmamed MF, Wang J, Melero I. Immunotherapy targeting 4-...