Mühl, H., Löffelhardt, W.: FEMS Microbiol. Lett.,13,9–12 (1982)Mühl H and Löfaelhardt W (1982) 4-hydroxyphenylpyruvate dioxygenase is bound to thylakoid membranes from the cyanobacterium Anacystis nidulans . FEMS Microbiol Lett 13: 9–12...
The primary structure of Pseudomonas 4-hydroxyphenylpyruvate dioxygenase was determined. Sequence degradation of the intact protein and of peptides from three different digests of the carboxymethylated protein established a 357-residue polypeptide chain with a free α-amino group. Hydroxylamine cleavage at...
Discovery of a potent, non-triketone type inhibitor of 4-hydroxyphenylpyruvate dioxygenase[J] . Shean-Woei Lin,Yun-Loung Lin,Tzu-Ching Lin,Ding-Yah Yang.Bioorganic & Medicinal Chemistry Letters . 2000 (11)Lin SW, Lin YL, Lin TC, Yang DY (2000) Discovery of a potent, non-triketone type...
Background: The enzyme 4-hydroxyphenylpyruvate dioxygenase (HPPD) is key in tyrosine catabolism. Inhibition of HPPD results in tyrosinemia and increased urinary excretion of 3 phenylketones: 4-hydroxyphenylpyruvate (HPPA), 4-hydroxyphenyllactate (HPLA), and 4-hydroxyphenylacetate (HPAA). A previous ...
4-Hydroxyphenylpyruvate dioxygenase (HPPD) is an important target for drug and herbicide development. Although the time-dependent behavior of HPPD inhibitors has been studied for decades, its structural basis and mechanism remain unclear. Herein, we report a detailed experimental and computational study...
HERBICIDESDYNAMIC simulationPROTEIN-protein interactionsBACKGROUND: 4‐Hydroxyphenylpyruvate dioxygenase (HPPD) herbicides control broadleaf and gramineous weeds with better crop safety for corn, sorghum and wheat. Multiple screening models in silico have been established to obtain novel lead compounds as...
4‐Hydroxyphenylpyruvate dioxygenase is bound to thylakoid membranes from the cyanobacterium Anacystis nidulansdoi:10.1111/j.1574-6968.1982.tb08216.xH MuehlWolfgang Loeffelhardt
HERBICIDES4‐Hydroxyphenylpyruvate dioxygenase (HPPD) plays a crucial role in the synthesis of nutrients needed to maintain optimal plant growth. Its level is closely linked to the extent of abiotic stress experienced by plants. Moreover, it is also the target of commercial herbicides. Therefore, ...
Tembotrione detoxification in 4‐hydroxyphenylpyruvate dioxygenase (HPPD) inhibitor‐resistant Palmer amaranth (doi:10.1002/ps.4786Küpper, AnitaPeter, FalcoZllner, PeterLorentz, LotharTranel, Patrick JBeffa, RolandGaines, Todd APest Management Science...
Molecular insights into the mechanism of 4‐hydroxyphenylpyruvate dioxygenase inhibition: enzyme kinetics, X‐ray crystallography and computational simulationsdoi:10.1111/febs.14747Lin, Hong‐YanYang, Jing‐FangWang, Da‐WeiHao, Ge‐FeiDong, Jiang‐Qing...