3DVA is implemented in the cryoSPARC software package.doi:10.1016/j.jsb.2021.107702Ali PunjaniDavid J. FleetJournal of Structural Biology
especially in the neighborhoods of the receptor binding domain (RBD) and N-terminal domain (NTD). We process 2,139 raw cryo-EM movies (EMPIAR-10516) in cryoSPARC to obtain 113,511 particle images (box size 256; pixel