OELH catalyzes the important conversion of cyclic 3-oxoadipate enol-lactone to linear 3-oxoadipate, which is finally transformed to citric acid cycle intermediates succinyl-CoA and acetyl-CoA. Structural analysis of the OELH from the proteobacterium Burkholderia xenovorans found in dimeric form suggest...
The catechol and protocatechuate branches of the 3-oxoadipate pathway, which are important for the bacterial degradation of aromatic compounds, converge at the common intermediate 3-oxoadipate enol-lactone. A 3-oxoadipate enol-lactone-hydrolyzing enzyme, purified from benzoate-grown cells of Rhodococc...