接收到3-Methyladenine (Autophagy Inhibitor, 3-MA)产品后,置于4°C温度下保存。 其他 Usbiological公司是美国著名的抗体和生化试剂供应商,生产世界上种类最多的抗体,用于Western Blot、免疫沉淀、免疫荧光、免疫组化和流式细胞术等多种检测方法。Usbiological公司现已拥有超过50,19234种抗体、抗原和生化产品,为科研...
结果表明,3-MA治疗显著降低了高尿酸血症小鼠肾脏中蜗牛和蛞蝓的升高表达(图4d–f)。通过以上一系列实验作者证明在HN中,3-MA是通过一种与抑制核转录因子相关的机制抑制肾EMT。 Fig 4.3-MA抑制自噬通过调节Snail和Slug两种转录因子阻断...
Autophagy Inhibitor, 3-MA,CAS:5142-23-4。在113出版物中被引用
Autophagy Inhibitor 3-MA Enhances Caspase-1-Independent or Ipaf-Independent Cell Death of Macrophages Infected with ShigellaToshihiko, SuzukiLuigi, FranchiClaudia, TomaHiroshi, AshidaMichinaga, OgawaYuko, YoshikawaHitomi, MimuroNaohiro, InoharaChihiro, Sasakawa...
[1] Miller S, et al. Finding a fitting shoe for Cinderella: searching for an autophagy inhibitor [J]. Autophagy. 2010, 6: 805-807. [2] Hou H, et al. Inhibitors of phosphatidylinositol 3'-kinases promote mitotic cell death in HeLa cells [J]. PLoS One. 2012; 7(4): e35665. ...
Autophagy Inhibitor, 3-MA-CAS 5142-23-4-Calbiochem 3-Methyladenine 自噬抑制剂,3-MA-CAS 5142-23-4-Calbiochem 3-甲基腺嘌呤 产品介绍: 产品说明 一般描述 一种广泛使用的细胞渗透性自噬隔离阻滞剂,可有效保护小脑颗粒细胞免于血清/钾缺乏后的凋亡。尽管也被成为III类PI3K抑制剂(在无细胞酶法测定中IC50= 4.5...
产品名称:Autophagy Inhibitor, 3-MA - CAS 5142-23-4 - Calbiochem产品型号:189490 The Autophagy Inhibitor, 3-MA, also referenced under CAS 5142-23-4, controls the biological activity of Autophagy.merck millipore,默克密理博,189490,Autophagy Inhibitor, 3-MA - CAS 5142-23-4 - Calbiochem ...
3-Methyladenine (3-甲基腺嘌呤;3-MA) 是 PI3K 的抑制剂。它通过抑制class III PI3K广泛作为自噬 (autophagy) 的抑制剂使用。 图1.3-Methyladenine化学结构 3-Methyladenine基础信息 中文名:3-甲基腺嘌;选择性PI3K抑制剂;PI3K抑制剂 英文名:3-Methyladenine, selective PI3K inhibitor;3-MA CAS号:5142-23-4 ...
ObjectiveThis study was to investigate the suppressive effects of autophagy inhibitor 3-MA on the proliferation of human retinal pigment epithelium cells (hRPECs) following high glucose culture. MethodsHRPECs were divided into control group, high-glucose group and 3-MA+ high glucose group.The cells...
of autophagy (lysosomal self-degradation) and apoptosis under various conditions. 3-MA inhibits autophagy by blocking autophagosome formation via the inhibition of type III Phosphatidylinositol 3-kinases (PI-3K). For use as an autophagy inhibitor, 3-MA is typically used at a concentration of 5 mM...