Cancer Res. 2005 Aug 1; 65 (15) :7023-30. [2]. Ueyama A, et al. Nonradioisotope assay of glucose uptake activity in rat skeletal muscle using enzymatic measurement of 2-deoxyglucose 6-phosphate in vitro and in vivo. Biol Signals Recept. 2000 Sep-Oct; 9 (5) :267-74. [3]. ...
proliferation.2-Deoxy-D-glucose(2DG),aglucoseanalog, targetsglucosemetabolismtodepletecancercellsofenergy.Inaddition,2DGincreasesoxidativestress, inhibitsN-linkedglycosylation,andinducesautophagy.Itcanefficientlyslowcellgrowthandpotently facilitateapoptosisinspecificcancercells.Although2DGitselfhaslimited...
The bifunctional autophagic flux by 2-deoxyglucose to control survival or growth of prostate cancer cells. Cancer Res. 2005 Aug 1;65(15):7023-30. PMID: 16061689 体外研究(细胞实验): 细胞类型(Cell types):MCF-7 cells 实验方法(Assay):For cell growth assay, MCF-7 cells were plated at 3 ...
2-Deoxy-D-glucose_醣酵解的抑制剂_154-17-6_Apexbio
Vivo.CancerResearch,2004,64:31-34. [4].ThomasMühlenberg,SusanneGrunewald,JürgenTreckmann,etal.Inhibitionof KIT-Glycosylationby2-DeoxyglucoseAbrogatesKIT-SignalingandCombinationwithABT-263 SynergisticallyInducesApoptosisinGastrointestinalStromalTumor.PLOSONE,2015, ...
2-Deoxy-D-glucose (2-DG) 是葡萄糖的类似物,是一种糖酵解抑制剂。2-Deoxy-D-glucose 具有抗病毒活性,还具有抑制细胞增殖、诱导细胞凋亡的活性。 规格价格库存数量 100 mg¥ 153现货 500 mg¥ 326现货 1 g¥ 413现货 5 g¥ 987现货
Due to limited availability of pharmacological therapies, triple-negative breast cancer (TNBC) is the subtype with worst outcome. We hypothesised that 2-Deoxy-D-Glucose (2-DG), a glucose analogue, may hold potential as a therapy for particularly aggressi
2-Deoxy-d-glucose (2DG) has been demonstrated to be a powerful agent for blocking and probing increased sugar metabolism in cancer cells [2]. Because of its similarity to glucose, 2-Deoxy-D-glucose inhibits glycolysis, but as chemically it is also 2-deoxymannose it is able to compete wit...
文献1,Yan J et al. The bifunctional autophagic flux by 2-deoxyglucose to control survival or growth of prostate cancer cells. Cancer Res. 2005 Aug 1;65(15):7023-30. PMID: 16061689 体外研究(细胞实验): 细胞类型(Cell types):MCF-7 cells ...
2-Deoxy-D-glucose 2-Deoxy-D-glucose is a glucose molecule which has the 2-hydroxyl group replaced by hydrogen, so that it cannot undergo further glycolysis. As such, it acts to competitively inhibit the production of glucose-6-PO4 from glucose at the phosphoglucoisomerase level.[2] In ...