2-脱氧-D-葡萄糖(CAS号:154-17-6),简称2DG,是一种具有独特结构和广泛生物活性的化学物质。其分子式为C6H12O5,分子量为164.16,呈白色至近白色固体状态。近年来,2DG在科研领域的应用逐渐受到重视,尤其在药物研发、疾病诊断和治疗等方面展现出巨大的潜力。 二、产品特性 物理性质:2DG为白色至近白色固体,易溶于...
运输条件:Evaluationsamplesolution:shipwithblueice Allotheravailablesize:shipwithRT,orblueiceuponrequest 生物活性 靶点:Others 信号通路:Hexokinase 产品描述: 2-Deoxy-D-glucose(2DG)(葡萄糖模拟物)是一个竞争性糖酵解的抑制剂[1-3]。细胞毒性试验中对KIT-阳性细胞株GIST882和GIST430的IC50值分别为0.5μM和...
2-Deoxy-D-glucose_醣酵解的抑制剂_154-17-6_Apexbio
[1]. 2-DG is readily transported into cells and is phosphorylated by hexokinase, but cannot be metabolized further and accumulates in the cell. This leads to ATP depletion and the induction of cell-death[2]. 2DG significantly suppresses proliferation, causes apoptosis and reduces migration of ...
D-2dGlc;nsc15193;deoxyglucose;2-deoxy-glucos;D-2-GLUCODESOSE;d-2-deoxyglucose;2-deoxy-d-glucos;2-Deoxy-D-mannose;D-Arabino-hexose, 2-deoxy-;arabino-Hexose, 2-deoxy-;D-Glucose, 2-deoxy-;9G2MP84A8W;(3R,4S,5R)-3,4,5,6-tetrahydroxyhexanal;2 Deoxyglucose;2 Deoxy D glucose;2 ...
2DG and glycolysis as therapeutic targets for status epilepticus Thomas P.Sutula,Nathan B.Fountain, inEpilepsy & Behavior, 2023 Abstract 2-deoxy-D-glucose(2DG) is a glucose analog differing from glucose only by removal of an oxygen atom at the 2 position, which prevents the isomerization of...
2-Deoxy-D-glucose (2DG),是一种葡萄糖类似物,作为竞争性糖酵解抑制剂[1]。 2-脱氧-d-葡萄糖 (2DG) 已被证明是一种强大的药物,可阻断和探测癌细胞中增加的糖代谢[2]。由于其与葡萄糖的相似性,2-脱氧-D-葡萄糖抑制糖酵解,但在化学上它也是 2-脱氧甘露糖,它能够在 N-连接糖基化的初始步骤中与生...
D-2dGlc;nsc15193;deoxyglucose;2-deoxy-glucos;D-2-GLUCODESOSE;d-2-deoxyglucose;2-deoxy-d-glucos;2-Deoxy-D-mannose;D-Arabino-hexose, 2-deoxy-;arabino-Hexose, 2-deoxy-;D-Glucose, 2-deoxy-;9G2MP84A8W;(3R,4S,5R)-3,4,5,6-tetrahydroxyhexanal;2 Deoxyglucose;2 Deoxy D glucose;2 ...
D-2dGlc;nsc15193;deoxyglucose;2-deoxy-glucos;D-2-GLUCODESOSE;d-2-deoxyglucose;2-deoxy-d-glucos;2-Deoxy-D-mannose;D-Arabino-hexose, 2-deoxy-;arabino-Hexose, 2-deoxy-;D-Glucose, 2-deoxy-;9G2MP84A8W;(3R,4S,5R)-3,4,5,6-tetrahydroxyhexanal;2 Deoxyglucose;2 Deoxy D glucose;2 ...
The best-studied candidate for a caloric-restriction mimetic, 2DG (2-deoxy-D-glucose), works by interfering with the way. 模拟限制摄入热量的最佳研究候选对象,2DG(2-脱氧-D-葡萄糖),通过干扰方式起作用。 分句-1 Cells process glucose in the way. 细胞以这种方式加工葡萄糖。 全句 The be...