18F-PIB、18F-THK5117和18F-THK523核素分子探针在医学领域的应用日益广泛，它们以独特的优势在疾病诊断和治疗中发挥着重要作用。18F-PIB作为一种先进的核素分子探针，以其高度的特异性和敏感性在神经退行性疾病的研究中崭露头角。这种探针能够精确地标记并追踪β-淀粉样蛋白，这对于阿尔茨海默病等疾病的早期诊断和病...
ImagingPurpose Visualization of the spatial distribution of neurofibrillary tangles would help in the diagnosis, prevention and treatment of dementia. The purpose of the study was to evaluate the clinical utility of [18F]THK-5117 as a highly selective tau imaging radiotracer....
18F-THK5117分子探针|分子靶点:Tau蛋白 中文名称:18F-THK5117 纯度:95%+ 储藏条件:-20°C下避光保存 用途:科研 状态:固体/粉末/溶液 介绍:β-淀粉样蛋白(amyloid β-protein,Aβ)、Tau蛋白是AD的重要标志物。 分子式 核素是指具有一定数目质子和一定数目中子的一种原子。同一种同位素的核性质不同的原子核,...
In the first dedicated small-animal PET study in 2 different transgenic tauopathy mouse models using the tau tracer 18F-THK5117, the temporal and spatial progression could be visualized in good correlation with gold standard assessments of tau accumulation. The serial small-animal PET method could ...
Thus, the use of noninvasive...doi:10.1016/j.jalz.2014.05.245Harada, RyuichiOkamura, NobuyukiFurumoto, ShozoTago, TetsuroYoshikawa, TakeoAkatsu, HiroyasuIwata, RenArai, HiroyukiYanai, KazuhikoKudo, YukitsukaElsevier Inc.Alzheimers & Dementia
Rowe, ChristopherTamagnan, GillesFodero-Tavoletti, MichelleOkamura, NobuyukiFurumoto, ShozoKudo, YukitsukaElsevier Inc.Alzheimer\"s & DementiaVillemagne V, Rowe C, Tamagnan G, et al. In vivo tau imaging with 18F- THK5105 and 18F-THK5117. Alzheimers Dement. 2014;10(suppl):P241....
The relationship between the ADAS-cog score and [18F]THK-5117 SUVR.Aiko, IshikiNobuyuki, OkamuraKatsutoshi, FurukawaShozo, FurumotoRyuichi, HaradaNaoki, TomitaKotaro, HiraokaShoichi, WatanukiYoichi, IshikawaTetsuro, Tago
Tashiro, ManabuYanai, KazuhikoKudo, YukitsukaArai, HiroyukiElsevier Inc.Alzheimers & DementiaIshiki A, Furumoto S, Harada R, et al. Accumulation of the novel tau imaging tracer 18F- THK-5117 is associated with brain atrophy in Alzheimer's disease. Alzheimer Dement. 2014; 10:131....
doi:10.1016/j.jalz.2014.05.223Okamura, NobuyukiHarada, RyuichiFurumoto, ShozoFurukawa, KatsutoshiIshiki, AikoTomita, NaokiTashiro, ManabuIwata, RenYanai, KazuhikoArai, HiroyukiElsevier Inc.Alzheimers & Dementia the Journal of the Alzheimers Association...
[18F]THK-5117-PET AND [11C]PIB-PET IMAGING IN IDIOPATHIC NORMAL PRESSURE HYDROCEPHALUS (INPH) IN RELATION TO CONFIRMED AMYLOID-β PLAQUES AND TAU IN BRAIN BIOPSIESTo evaluate the suitability of 11C-PIB and 18F-flutemetamol for small animal PET imaging and for longitudinal follow-up of beta-...