The dehydrogenase form of 11 尾-hydroxysteroid dehydrogenase (11-DH) which catalyzes the oxidation of the biologically active steroid, corticosterone, to its inactive metabolite, 11-dehydrocorticosterone, is found in rat brain. The distribution and localization of 11-DH-like labeling in the rat ...
WO2001090090A1 2001-11-29 INHIBITORS OF 11-BETA-HYDROXY STEROID DEHYDROGENASE TYPE 1Other References: STN search report: Zhurnal Organicheskoi Khimii (1974), 10(4), 761-5. STN search report: EP 399814 (1992). Markownikow “Beilstein Institut zur Foerderung der Chemischen Wissenschaften, Fra...
Novel compounds are provided which are 11-beta-hydroxysteroid dehydrogenase type I inhibitors. 11-beta-hydroxysteroid dehydrogenase type I inhibitors are useful in treating, prevent
As is known, the inhibition of intracellular enzyme 11-beta-hydroxysteroid dehydrogenase type 1 (11βHSD1) has been extensively studied as a therapeutic mechanism for the treatment of type 2 diabetes mellitus (T2DM). Compound 185 (Fig. 19) containing 5-oxazole at the 4-pos...
OBJECTIVE: Selective inhibitors of 11beta-hydroxysteroid-dehydrogenase type I may be of therapeutical interest for two reasons: i) 9alpha-Fluorinated 11-dehydrosteroids like 11-dehydro-dexamethasone (DH-D) are rapidly activated by human kidney 11beta-hydroxysteroid-dehydrogenase type II (11beta-HSD-...
HSD11B1L, CT (HSD11B1L, HSD3, SCDR10, Hydroxysteroid 11-beta-dehydrogenase 1-like protein, 11-beta-hydroxysteroid dehydrogenase type 3, Short-chain dehydrogenase/reductase 10)供应商 MyBioSource产品货号 MBS642231产品报价 ￥询价/0.2mL ￥询价/5x0.2mL ￥询价/其它规格产品说明书 点击查看购买...
世联博研公司现货供应abbexa品牌订货号为Catalogue No: abx308275的Hydroxysteroid 11-Beta-Dehydrogenase 1 Like Protein (HSD11B1L) Antibody (Biotin)产品
Reagents which regulate human 11 beta-hydroxysteroid dehydrogenase 1-like enzyme and reagents which bind to human 11 beta-hydroxysteroid dehydrogenase 1-like enzyme gene products can play a role in preventing, ameliorating, or correcting dysfunctions or diseases including, but not limited to CNS ...
Voice MW, Seckl JR, Edwards CR, Chapman KE: 11-hydroxysteroid dehydrogenase type 1 expression in 2S FAZA hepatoma cells is hormonally regulated: a model system for the study of hepatic glucocorticoid metab- olism. Biochem J 317:621- 625, 1996...
Reagents which regulate human 11 beta-hydroxysteroid dehydrogenase 1-like enzyme and reagents which bind to human 11 beta-hydroxysteroid dehydrogenase 1-like enzyme gene products can play a role in preventing, ameliorating, or correcting dysfunctions or diseases including, but not limited to CNS ...