Kidney microsomal 25- and 1α- hydroxylase in vitamin D metabolism: Catalytic properties, molecular cloning, cellular localization and expression during development. Biochimica et Biophysica Acta 2002 ; 1580:133 - 144Hosseinpour F, Norlin M, and Wikvall K (2002) Kidney microsomal 25- and 1alpha...
(2002) Kidney microsomal 25- and 1alpha-hydroxylase in vitamin D metabolism: catalytic properties, molecular cloning, cellular localization and expression ... F Hosseinpour,M Norlin,K Wikvall - 《Biochimica Et Biophysica Acta Molecular & Cell Biology of Lipids》 被引量: 0发表: 2002年 Kidney mi...
Evidence for 54-kD protein in chicken kidney as a cytochrome P450 with a high molecular activity of 25-hydroxyvitamin D3 1 alpha-hydroxylase. Conversion of 25-hydroxyvitamin D3 (25(OH)D3) to the active vitamin D3, 1α,25-dihydroxyvitamin D3 (1α,25(OH)2D3) is catalyzed by 25(OH)D...
Vascular Calcification Induced by Chronic Kidney Disease Is Mediated by an Increase of 1alpha-Hydroxylase Expression in Vascular Smooth Muscle Cells. J. Bone... N Torremadé,M Bozic,S Panizo,... - 《Journal of Bone & Mineral Research》 被引量: 2发表: 2016年 Role of Hyperphosphatemia and ...
Gao XH, Dwivedi PP, Choe S, Alba F, Morris HA, Omdahl JL, May BK 2002 Basal and parathyroid hormone induced expression of the human 25-hydroxyvitamin D 1alpha- hydroxylase gene promoter in kidney AOK-B50 cells: Role of Sp1, Ets and CCAAT box protein binding sites. Int J Biochem Cell ...
The murine homologue of the 25-hydroxyvitamin D [25(OH)D] 1alpha-hydroxylase gene [1alpha(OH)ase; Cyp27bl], which is mutated in humans with vitamin D-dependent rickets type I (VDDR-I; also known as pseudovitamin D-deficiency rickets [PDDR]) was cloned and characterized. Like the huma...
hydroxylase (IC50 = 0.49 µM).{26060} Inhibition of HIF prolyl hydroxylase by BAY-85-3934 has been shown to increase endogenous production of erythropoietin.{26060} This compound has been investigated in clinical trial for treatment of patients with anemia associated with chronic kidney disease ...
egocalciferol (D2), and calcifediol (25- hydroxy vitamin D3, which need 1-alpha hydroxylase to be activated, 1-alpha-ergocalciferol, also known as doxercalciferol, is a synthetically manufactured vitamin D analog used for treatment of secondary hyperparathyroidism (SHPT) in chronic kidney disease ...
25-Hydroxyvitamin D3 1alpha-hydroxylase expression in breast cancer and use of non-1alpha-hydroxylated vitamin D analogue The cytochrome P450 mitochondrial enzyme 25-hydroxyvitamin D3 1alpha-hydroxylase (1alpha-hydroxylase) of renal tubule cells hydroxylates the major circulat... S Ulrika,H Pernille...
CT also increased the expression of CYP27B1 mRNA in the kidney of normocalcemic TPTX rats. Conversion of serum [3H]1alpha,25(OH)2D3 from 25-hydroxy[3H]vitamin D3 in vivo was also greatly increased by the injection of CT into sham-TPTX rats and normocalcemic TPTX rats, but not ...