[3] Zepeda-Cervantes J, Ramírez-Jarquín JO, Vaca L. Interaction Between Virus-Like Particles (VLPs) and Pattern Recognition Receptors (PRRs) From Dendritic Cells (DCs): Toward Better Engineering of VLPs. Front Immunol. 2020 Jun; 11:1100. [4] Mellid-Carballal R, Gutierrez-Gutierrez S, Riv...
导读 病毒样颗粒(Virus-like particles, VLP)是自组装、非复制、非致病性、高度组织的超分子纳米颗粒,由一种或多种病毒衣壳蛋白自发自组装产生。由于VLP 的非传染性与可定制性,此类疫苗的研究与开发也变得更为火热。但VLP的大规模生产也存在诸多挑战,如保证产品的高纯度、改善结构均匀性和胶体稳定性。基于VLP的疫苗...
病毒样颗粒疫苗(Viruslikeparticles,VLP)简介病毒样颗粒疫苗(Viruslikeparticles,VLP)简介是一类具有病毒结构,没有病毒复制能力,较减毒疫苗和以病毒为载体的疫苗更加安全的疫苗种类。以病毒样颗粒形成的疫苗抗原可有效激发免疫应答和免疫保护效果,研发病毒样颗粒疫苗已成为埃博拉疫苗发展的重要方向。...阅读全文病毒样...
The virus like particles (VLPs) in insect cells. 目的 在昆虫细胞中同时表达HCV的核心蛋白C和包膜蛋白 (E1、E2 )以形成病毒样颗粒 (VLP)。 3. To obtain the virus like particles (VLPs) of human papillomavirus type 4 (HPV4), the cloned vector pUHPV4 L 1 containing the L 1 gene was diges...
通讯作者:**利,E-mail:ylyu@mail.jlu.edu.cn・专家论坛・病毒样颗粒抗原的表达、纯化、组装和鉴定于永利吉林大学白求恩医学院免疫系,吉林长春130021摘要:病毒样颗粒(Virus-likeparticles,VLPs)是由一种或多种病毒结构蛋白组装成的的颗粒,具有与病毒颗粒相似的外部结构和抗原性,但不含病毒基因。以预防乙型肝炎...
Virus-like particles (VLPs) are a novel approach for viral vac- cines containing viral antigen proteins that form a virus-like struc- ture but lack the viral genome [7,8]. They do not have replication ability. Previous studies showed Newcastle Disease Virus (NDV) RSV VLPs could induce ...
病毒样颗粒The baculovirus expression system was employed to prepare the virus-like particles (VLPs) of human parvovirus B19. The synthesized VP2 gene of B19 was inserted into the multi-cloning site (MCS) of pFastBac1 vector; the resulting plasmid was transferred to the Escherichia coli DH10Bac...
病毒样颗粒疫苗(Viruslikeparticles,VLP)简介病毒样颗粒疫苗(Viruslikeparticles,VLP)简介是一类具有病毒结构,没有病毒复制能力,较减毒疫苗和以病毒为载体的疫苗更加安全的疫苗种类。以病毒样颗粒形成的疫苗抗原可有效激发免疫应答和免疫保护效果,研发病毒样颗粒疫苗已成为埃博拉疫苗发展的重要方向。...阅读全文流感病毒...
Virus-like particles (VLPs) is a non-nucleic acid virus particles,with the same morphology to the natural virus particles. 病毒样颗粒(virus-like particles,VLPs)是一种不含核酸的空心病毒颗粒,形态结构上与天然病毒颗粒极其相似。 更多例句>> 6...
2.The virus like particles (VLPs) in insect cells.目的 在昆虫细胞中同时表达HCV的核心蛋白C和包膜蛋白 (E1、E2 )以形成病毒样颗粒 (VLP)。 3.To obtain the virus like particles (VLPs) of human papillomavirus type 4 (HPV4), the cloned vector pUHPV4 L 1 containing the L 1 gene was digeste...