Production of tumor necrosis factor (TNF)-alpha and interferon (IFN)-gamma, two important cytokines involved in the immune responses to hepatitis B virus (HBV) infection, may be influenced by gene polymorphisms of TNFA and PD1. This study determined the associations of serum TNF-alpha and IFN-...
3.2. Inhibition of Cytokines Related to Immune Response by MB-2006 in TNF-α/IFN-γ-Induced HaCaT Keratinocytes Pro-inflammatory cytokines, pivotal in the context of AD, are known for their role in promoting allergic reactions and triggering various biological effects within the immune system [6]...
Sertoli cells stimulated with TNF-alpha and IFN-gamma markedly increase the expression of both soluble and membrane-bound Fas in a dose-dependent manner. The up-regulated membrane-bound Fas protein is functionally active because it induces a significant level of Sertoli cell death in the presence ...
TNF-α/IFN-γ was used to induce inflammation in HaCaT cells, which is representative of inflammatory skin disease in an in vitro model. We performed real-time PCR to confirm the inhibitory effect of α-boswellic on the TNF-α/IFN-γ-induced cytokines and chemokine expression levels in HaCaT...
TNF-alpha and IFN-gamma cooperate in the activation of macrophages. TNF-alpha-dependent activation of NF-kappaB is stronger in the presence of IFN-gamma. STAT-1alpha associates with TNFR1 in TNF-alpha-treated cells, and this association attenuates TNF-alpha-mediated NF-kappaB activation. We hyp...
VCAM-1 expression by HEC was upregulated by cytokine pretreatment and the effects were ordered: IFN-gamma > TNF-alpha > IL-1 beta. The results ... MJ May,G Entwistle,MJ Humphries,... - 《Journal of Cell Science》 被引量: 111发表: 1993年 Natural history of murine γ-herpesvirus infect...
Lipoarabinomannan-specific TNF-alpha and IFN-gamma as markers of protective immunity against tuberculosis: a cohort study in an endemic setting 喜欢 0 阅读量: 27 作者:Legesse,Mengistu,Bjune,Gunnar,Mihret,Adane,Belay,Mulugeta,Bekele,Yonas
Human IFN-gamma protein, His Tag、Mouse IFN-gamma protein, His Tag:Ⅱ型干扰素IFN-γ广泛参与免疫及炎症应答反应。IFN-γ信号通路的适当激活可促进巨噬细胞的激活,介导宿主对病原体的防御功能,同时,IFN-γ信号通路还可以在抗肿瘤免疫中发挥免疫调控作用。 新品详情: 产品提供形式:冻干粉形式,在室温条件下非常...
Kinetics of TNF-alpha and IFN-gamma mRNA expression in islets and spleen of NOD mice Insulin-dependent diabetes mellitus is caused by autoimmune destruction of pancreaticcells. Non-obese diabetic (NOD) mice spontaneously develop diabetes si... Ventura-Oliveira,D.,Vilella,... - 《Brazilian Journal...
Antisense oligonucleotides complementary to Stat1 alpha mRNA were introduced in CH235-MG astroglioma cells by transient transfection; such treatment inhibited both constitutive and IFN-gamma-enhanced expression of Stat1 alpha. IFN-gamma-induced class II MHC expression was also inhibited in cells exposed ...