CONCLUSIONS: TNF-alpha(/IFN-gamma) treatment up-regulates the expression of the NOD2 gene in intestinal epithelial cells and subsequently increases their LPS susceptibility. Together with the mutation-derived truncation and functional change of the NOD2 protein, this could be part of the complex ...
Human TNF-alpha protein:肿瘤坏死因子-α(TNF-α)是一种涉及到系统性炎症的细胞因子,主要由巨噬细胞分泌。其主要功能是调节免疫细胞,作为一种内源性致热源,可以导致发热,引起细胞凋亡,阻止肿瘤发生和病毒复制等。其功能失调被认为和很多疾病相关,比如阿尔兹海默症、银屑病、癌症、重度抑郁、肠炎等。TNF-a 是细胞信...
FluoroSpot Plus: Human IFN-gamma/TNF-alpha供应商 Mabtech产品货号 FSP-0109-2产品报价 ￥询价/2plates产品说明书 点击查看购买方式 银行转账、电汇、支票、现金,在线支付宝及网银支付,或直接与我们电话联系400-6800-868。产品新闻背景资料 干扰素-Y(IFN-Y)主要由活化的T细胞和NK细胞产生。它是一种促炎细胞因子,...
Taken together, our data suggest a possible regulatory role of TNF-alpha and IFN-gamma on Fas-mediated apoptosis in the testis through disruption of the balance between different forms of Fas. 展开 关键词: CTLA-4 autoimmune disease regulatory T cell CD25 self-tolerance ...
IFN-gamma and TNF-alpha, two cytokines known to be present in the insulitis lesion of NOD mice, or cAMP which can induce B7-1 expression on B ... LA Stephens,TWH Kay - 《International Immunology》 被引量: 71发表: 1995年 Kinetics of TNF-alpha and IFN-gamma mRNA expression in islets ...
Cicek Hocaoglu,Birgul Kural,Rezzan Aliyazicioglu.IL-1 beta, IL-6, IL-8, IL-10, IFN-gamma, TNF-alpha and its relationship with lipid parameters in patients with major depression.Metabolic Brain Disease. 2012Hocaoglu C, Kural B, Aliyazicioglu R, Deger O, ...
(1999) The modulating effects of proinflammatory cytokines interferon-gamma (IFN-c) and tumour necrosis factor-alpha (TNF-a), and immunoregulating cytokines IL-10 and transforming growth factor-beta (TGF-b), on anti-microbial activity of murine peritoneal macrophages against Mycobacterium avium-...
FluoroSpot测定是ELISpot测定的创造性发展并且使用荧光检测而不是比色法。这允许同时检测几种分析物,这是一个主要优点。该试剂盒非常适合希望获得方便检测且最小化检测可变性的用户。它能够计数分泌一种,两种或三种分析物的细胞。该试剂盒包括预先涂有单克隆捕获抗体的低
Rat mast cell lines (hybrid rat mast cells, HRMC, and rat cultured mast cells, RCMC) and mast cells from the rat body cavity were used to test the hypothesis that IFN-α/β and IFN-γ inhibit tumor necrosis factor α (TNF-α)-mediated cytotoxicity by depressing...
Perforin and Fas induced by IFNγ and TNFα mediate beta cell death by OT-I CTL NL, Mariana L, Chong MM, Trapani JA, Kay TW, Thomas HE: Perforin and Fas induced by IFNgamma and TNFalpha mediate beta cell death by OT-I CTL... MD Mckenzie,NL Dudek,L Mariana,... - 《Internationa...