Alpha-Alkylation by SN1-Type ReactionsAlpha-Alkylation by SN1-Type ReactionsBrønsted acidscarbocationschiral thioureasenamine catalysisLewis acidsorganocatalysisThis chapter contains sections titled: * SN1-Type Nucleophilic Reaction by Generation of Carbocations * Organocatalytic Stereoselective SN1-Type Rea...
Shim, Ruthenium-catalyzed regioselective alpha-alkylation of ketones with primary alcohols, Tetrahedron Lett., 2002, 43, 7987-7989.Chan Sik Cho,Bok Tae Kim,Myung Jin Lee,Tae-Jeong Kim,Sang Chul Shim. Ruthenium-Catalyzed Regioselectiveα-Alkylation of Ketones: The First Alkyl-Group Transfer from...
The invention discloses a synthesis method for alpha-alkylation by catalyzing secondary amine by using visible light. The synthesis method comprises the following steps: (1) adding inorganic metal salt and N-aryl glycine ester into an organic solvent, thereby obtaining a solution A; (2) adding ...
摘要: A process for alkylating the alpha position of the 8-acyl side chain in mevinolin and analogs thereof is disclosed. The process proceeds with a single charge of base and alkyl halide to give products with a pharmaceutically acceptable purity....
phase transfer catalysis;asymmetric catalysis;salen complexes;alkylation;amino acids 1. Introduction Chiral salen transition metal complexes have a significant role in the stereoselective synthesis being efficient chiral catalysts usable in a plethora of asymmetric transformations [1,2,3,4]. Their simple ...
Figure 1. Substrate scope for the alkylation of aromatic ketones using allylic alcohols. Inspired by the reaction results of ketones and allylic alcohol, we envisioned that by replacing allylic alcohols with α,β-unsaturated ketones, the alkylation reactions may take place under simpler reaction con...
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摘要: A process for the alpha -monoalkylation of arylacetonitriles, arylacetoesters and arylacetic acids with dialkyl carbonates in liquid phase, in the presence of bases at temperatures ranging from about 100 DEG C to about 270 DEG C.收藏...
ChemInform Abstract: REDUCTION AND REDUCTIVE ALKYLATION OF ALPHA-TERT.-BUTYLTHIO CARBONYL COMPOUNDS, AN EFFICIENT METHOD FOR STEPWISE ALPHA-ALKYLATION OF ESTERS... S.,KAMATA,S.,... - 《Chemischer Informationsdienst》 被引量: 0发表: 1974年 ChemInform Abstract: REDUCTION AND REDUCTIVE ALKYLATION OF ...
(thio)urea alpha-aminoalkylation with isobut - yraldehyde and sec aminesN,N'-disubstd. (thio)ureas, useful as vulcanisation accelerators, rubber stabilisers, textile assistants and lubricating oil additives, have formula X=C(NH-CH(CH-(CH3)2)NRR')2 (where R and R' are 1-4C alkyl or...