芋螺毒素u-Conotoxin GIIIA,u-Conotoxin GIIIB| MU-CONOTOXIN GIIIB,140678-12-2 基本参数: 名称:芋螺毒素u-Conotoxin GIIIA 英文名:u-Conotoxin GIIIB| MU-CONOTOXIN GIIIB 编号: CAS号: 140678-12-2 分子式:C101H175N39O30S7 分子量:2640.17 基本信息: 品牌:固拓 外观性状:白色粉末 纯度(HPLC):≥98.0...
Visit ChemicalBook for more information on MU-CONOTOXIN GIIIA (CAS 86394-16-3), including its chemical and physical properties, structure, melting point, boiling point, density, molecular formula, molecular weight, uses, prices, suppliers, and safety det
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Choudhary G,,Aliste M P,Tieleman D P,et al.Docking of mu-Conotoxin GIIIA in the sodium channel outer vestibule. Channels(Austin) . 2007Choudhary G,,Aliste M P,Tieleman D P,et al.Docking of mu-Conotoxin GIIIA in the sodium channel outer vestibule. Channels(Austin) . 2007...
mu-Conotoxin GIIIA, a 22 amino acid peptide paralytic toxin which inhibits the muscle voltage-activated sodium channels, was synthesized by a solid phase method. No purification of intermediates was necessary for the synthesis, and a simple air oxidation of the deprotected crude peptide gave the ...
Name:Mu-Conotoxin Giiia (Related Reference) Synonyms: geographutoxin I; H-ARG-ASP-CYS-CYS-THR-HYP-HYP-LYS-LYS-CYS-LYS-ASP-ARG-GLN-CYS-LYS-HYP-GLN-ARG-CYS-CYS-ALA-NH2; M-CONOTOXIN GIIIA; MU-CGTX GIIIA; MU-CONOTOXIN GIIIA; MU-CONOTOXIN GIIIA, CONUS GEOGRAPHUS; Safety...
The tetradomain voltage-gated sodium channels from rat skeletal muscle (rSkM1) and from human heart (hH1) possess different sensitivities to the 22-amino-acid peptide toxin, mu-conotoxin GIIIA (mu-CTX). rSkM1 is sensitive (IC50 = 51.4 nM) whereas hH1 is relatively resistant (IC50 = 5700...
Active site of ,u-conotoxin GIIIA, a peptide blocker of muscle sodium channels. J. Biol Chem. 266:16989-16991.Sato, Kazuki,Ishida, Yukisato,Wakamatsu, Kaori,Kato, Rika,Honda, Hiromi,Ohizumi, Yasushi,Nakamura, Hideshi,Ohya, Masanao,Lancelin, Jean-Marc,Kohda, Daisuke,Inagaki, Fuyuhiko.Active...
mu-conotoxin GIIIA interactions with the voltage-gated Na+ channel predict a clockwise arrangement of the domains. J Gen Physiol 2000;116:679-90.Dudley SC, Chang N, Hall J, Lipkind GM, Fozzard HA, and French RJ (2000) Mu conotoxin GIIIA interactions with the coltage-gated Na channel ...
μ-conotoxin GIIIAsodium channelstwitch contractionConotoxin GIIIA, a peptide toxin from the cone snail, blocks muscle-type sodium channels. Thr-5 of -conotoxin GIIIA, located on the opposite side of the active site in the globular molecule, was replaced by Cys to which the bulky tags were ...