The Zyprexa IM preparation is only for acute agitation associated with schizophrenia and bipolar I mania in adults. Zyprexa Relprevv IM is only available through a restricted distribution program, and the prescriber, healthcare facility, patient, and pharmacy must all be enrolled in the Zyprexa ...
1.4 ZYPREXA IntraMuscular: Agitation Associated with Schizophrenia and Bipolar I Mania ZYPREXA IntraMuscular is indicated for the treatment of acute agitation associated with schizophrenia and bipolar I mania. Efficacy was demonstrated in 3 short-term (24 hours of IM treatment) placebo-controlled trials...
The efficacy of intramuscular olanzapine for injection in controllingagitation in these disorders was demonstrated in a dose range of 2.5 mg to 10 mg. The recommended dose in these patients is 10 mg. A lower dose of 5 or7.5 mg may be considered when clinical factors warrant [seeClinical Studi...
Dose group differences have been observed for weight, fasting triglycerides and prolactin elevation for ZYPREXA RELPREVV [seeWARNINGS AND PRECAUTIONS]. A dose group difference for oral olanzapine has been observed for fatigue, dizziness, weight gain and prolactin elevation. In a single 8-week randomize...
Two deaths have been reported occurring 3 to 4 days after receiving the appropriate dose of the extended-release IM suspension. In these patients, very high olanzapine blood levels were reported after death. A study undertaken to determine the cause of the elevated drug levels in these 2 deaths...
Dose Selection For Agitated Adult Patients With Schizophrenia And Bipolar I Mania The efficacy of intramuscular olanzapine for injection in controllingagitation in these disorders was demonstrated in a dose range of 2.5 mg to 10 mg. The recommended dose in these patients is 10 mg. A lower dose ...
Extended-release IM injection: Very common (10% or more): Plasma prolactin level elevation (up to 30%) Uncommon (0.1% to 1%): Gynecomastia/male breast enlargement[Ref]In clinical studies, changes in prolactin levels were found to be statistically significantly different based on dose, higher ...
Dose Selection For Agitated Adult Patients With Schizophrenia And Bipolar I Mania The efficacy of intramuscular olanzapine for injection in controllingagitation in these disorders was demonstrated in a dose range of 2.5 mg to 10 mg. The recommended dose in these patients is 10 mg. A lower dose ...
Dose Selection For Agitated Adult Patients With Schizophrenia And Bipolar I Mania The efficacy of intramuscular olanzapine for injection in controllingagitation in these disorders was demonstrated in a dose range of 2.5 mg to 10 mg. The recommended dose in these patients is 10 mg. A lower dose ...
Dose Selection For Agitated Adult Patients With Schizophrenia And Bipolar I Mania The efficacy of intramuscular olanzapine for injection in controllingagitation in these disorders was demonstrated in a dose range of 2.5 mg to 10 mg. The recommended dose in these patients is 10 mg. A lower dose ...