While there is no body of evidence to answer the question of how long a patient treated with ZYPREXA and fluoxetine in combination should remain on it,it is generally accepted that treatment resistant depression (major depressive disorder in adult patients who do not respond to 2 separate trials ...
Alcohol— Ethanol (45 mg/70 kg single dose) did not have an effect on olanzapine pharmacokinetics. The co-administration of alcohol (i.e., ethanol) with olanzapine potentiated the orthostatic hypotension observed with olanzapine [see Drug Interactions (7.2)]. Inhibitors of CYP1A2 Fluvoxamine:...
临床试验中,接受奥氮平治疗的患者出现有临床意义的QTc间期延长(基线QTcF500毫秒)并不常见(0.1%-1%),和安慰剂相比,没有统计学差异。但与其他抗精神病药一样,奥氮平与其他已知可以延长QTc间期的药物合用时要谨慎,尤其是在老年患者、先天性长QT综合征患者、充血性心脏衰竭患者、心肌肥厚、低钾血症或低镁血症的患者。
Ethanol (45 mg/70 kg single dose) did not have an effect on olanzapine pharmacokinetics. The co-administration of alcohol (i.e., ethanol)with olanzapine potentiated the orthostatic hypotension observed with olanzapine [seeDRUG INTERACTIONS]. Inhibitors Of CYP1A2 Fluvoxamine, a CYP1A2 inhibitor, d...
Oral olanzapine should be administered on a once-a-day schedule without regard to meals, generally beginning with 10or 15 mg. Dosage adjustments, if indicated, should generally occur at intervals of not less than 24 hours, reflecting the procedures in the placebo-controlledtrials. When dosage adj...
Oral olanzapine should be administered on a once-a-day schedule without regard to meals, generally beginning with 10or 15 mg. Dosage adjustments, if indicated, should generally occur at intervals of not less than 24 hours, reflecting the procedures in the placebo-controlledtrials. When dosage adj...
Oral olanzapine should be administered on a once-a-day schedule without regard to meals, generally beginning with 10or 15 mg. Dosage adjustments, if indicated, should generally occur at intervals of not less than 24 hours, reflecting the procedures in the placebo-controlledtrials. When dosage adj...