Zynlonta dosing information Usual Adult Zynlonta Dose for Lymphoma: 0.15 mg/kg IV over 30 minutes on Day 1 of each cycle (every 3 weeks) for 2 cycles, then 0.075 mg/kg IV over 30 minutes every 3 weeks for subsequent cycles General dosing information ...
If dosing is delayed by more than 3 weeks due to toxicity related to ZYNLONTA®, reduce subsequent doses by 50%. If toxicity reoccurs following dose reduction, consider discontinuation. Note: If toxicity requires dose reduction following the second dose of 0.15 mg/kg (C2D1), the patient sh...
Cmax = Maximum observed serum concentration; AUCtau = Area under curve over the dosing interval * Data presented as mean and coefficient of variation (CV %) Cycle 2 2,911 (35.3%) 21,665 (54.1%) Steady state 1,776 (32.1%) 16,882 (38.2%) Distribution The mean (CV%) of loncastux...
Zynlonta (loncastuximab tesirine-lpyl) - Uses, Side Effects, and More Medically Reviewed by Shawn Bookwalter, MS, PharmD, BCPS, MSHI on Jul 13, 2024 | Written by Dena Westphalen, PharmD Common Brand Name(s): Zynlonta Common Generic Name(s): loncastuximab tesirine-lpyl Pronunciation: ...