Combination therapy of zonisamide and bupro- pion for weight reduction in obese women: a preliminary, rand- omized, open-label study. J Clin Psychiatry 2007; 68: 1226–9. 3. McElroy SL, et al. Zonisamide in the treatment of binge eating disorder with obesity: a randomized controlled ...
oil elimination. Meridia® (sibutramine hydrochloride) is a serotonin, norepinephrine and to a lesser extent dopamine re-uptake inhibitor; its side effects include dry mouth, anorexia, insomnia, constipation and headache. Meridia® is recommended for obese patients with an initial body mass index ...
Some clinicians recommend closely monitoring zonisamide concentrations and adjusting zonisamide dosage as necessary in pregnant women.LactationDistributes into human milk. Discontinue nursing or the drug.Pediatric UseSafety and efficacy not established in children <16 years of age. However, the drug has ...
There are limited data from the use of zonegran in pregnant women and the potential risk in terms of reproductive toxicity for humans is unknown. Zonisamide must not be used during pregnancy unless it is required based on the clinical condition of the patient. In such cases, the dose of zon...
Zonisamide should not be abruptly discontinued and should be administered with caution to patients with hepatic dysfunction and pregnant women. Blood zonisamide concentrations may alter with concomitant administration of other antiepileptic drugs. Indeed, blood AUC values for zonisamide were greater in the ...
There are limited data from the use of zonegran in pregnant women and the potential risk in terms of reproductive toxicity for humans is unknown. Zonisamide must not be used during pregnancy unless it is required based on the clinical condition of the patient. In such cases, the dose of zon...