ZO-1 基因可能成为新的分子标志,为临床早期诊断、疗效判断、预后评价、微小残留检测提供新的指标。 ZO-1 gene methylation status and its clinical significance in children with non- Hodgkin lymphoma , YANG Ming-Juan, MENG Jian-Hui, ZHU Xiu-Li, CHEN Jian Abstract:ObjectiveTo investigate the methylation ...
甲基化Objective To evaluate the clinical significance of methylation status in promoter region of Z0-1 gene in different phase of disease progression of chronic mylogenous leukemia ( CML) .Method Methylated polymerase chain reaction ( MS-PCR) method was used to detect the methylation status in ...
2014 NHL cases carrying methylated ZO-1 gene had no mRNA expression of ZO-1, while all children in the control group had mRNA expression of ZO-1. There was no linear relationship between the total number of peripheral blood leukocytes and ZO-1 gene IOD (r=0.093, P=0.575); a positive ...
该支架蛋白的多结构域,包括突触后密度95/盘大/带状闭塞区(PDZ)结构域、Src同源结构域(SH3)结构域、鸟苷酸激酶(GuK)结构域和独特的(U)基序,都有助于协调跨膜蛋白、胞浆蛋白和F-肌动蛋白的结合它们是紧密连接功能所必需的。选择性剪接导致编码不同亚型的多个转录变体[由RefSeq提供,2017年8月] This gene encod...
Gene ID (NCBI) 7082 RRID AB_10733242 Conjugate Unconjugated Form Liquid Purification Method Antigen affinity purification UNIPROT ID Q07157 Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Storage Conditions Store at -20°C. Stable for one year after shipment. Aliquoting is...
membrane surface of intercellular tight junctions. ZO-1 may be involved in signal transduction at cell-cell junctions. Two transcript variants encoding distinct isoforms have been identified for the ZO-1 gene. Diseases associated with ZO-1 dysfunction include Celiac Disease and Congenital Nephrotic ...
membrane surface of intercellular tight junctions. ZO-1 may be involved in signal transduction at cell-cell junctions. Two transcript variants encoding distinct isoforms have been identified for the ZO-1 gene. Diseases associated with ZO-1 dysfunction include Celiac Disease and Congenital Nephrotic ...
Two transcript variants encoding distinct isoforms have been identified for the ZO-1 gene. Diseases associated with ZO-1 dysfunction include Celiac Disease and Congenital Nephrotic Syndrome. Tight junction protein 1; tight junction protein 1 (zona occludens 1); Tight junction protein ZO-1; ZO-1;...
Key words zo,1 gene; m ethylation; m yelodysplastic syndrom e; differential diagnosis JExpHematol 2011; 19( 1): 76- 80 骨髓增生异常综合征(myelodysplastic syn(drom e)M D S)为造血干细胞克隆性疾病,主要表现为乏力、出血、贫血,外周血中一系或多系血细胞减少,骨髓细胞增生活跃,并有病态造血,易与...
suspected MDS patients manifested hypermeth ylation status of zo一1 gene (7/20 ) ,2 were followed up for 1 year and tr an sf orm ed into MD S . It is conclud ed th at relati vely high hypermeth y lati on rate of zo —l promoter is obser ved in M D S —R A .an d...