Type 2 diabetes mellitus (T2DM) characterized by insulin resistance has become a serious health threat. Chronic inflammation is believed to play a pivotal role in the development of T2DM. Previous study has shown that HO-1 plays an anti-inflammatory role, suggesting HO-1 inhibition could be an...
Triterpenoid CDDO-ME is highly synergistic with the HO-1 inhibitor SMA-ZNPP in imatinib-resistant CML cellsK., GleixnerH., HerrmannK., BlattK., SchuchW., PicklM., KonoplevaM., AndreeffP., Valent
Effect on cell cycle distribution after treatment with ZnPP or HO-1 siRNA in crotonaldehyde-stimulated HepG2 cells.Seung Eun LeeHana YangSeong Il JeongYoungHo JinCheungSeog ParkYong Seek Park
Schematic depiction of proposed pathophysiology of tumor killing induced by SSRBCs and the HO-1 inhibitor ZnPP.David S. TermanBenjamin L. VigliantiRahima ZennadiDiane FelsRichard J. BorutaHong YuanMathew R. DreherGerald GrantZahid N. Rabbani...
Remote ischemic preconditioning induced HO-1 to increase autophagy, but the inhibition of HO-1 by Znpp decreased autophagy.Yun WangJian ShenXuanxuan XiongYonghua XuHai ZhangChangjun HuangYuan TianChengyu JiaoXuehao WangXiangcheng Li
糖尿病肾脏疾病血红素加氧酶氧化应激核相关因子2目的观察模拟2型糖尿病大鼠肾脏血红素加氧酶(HO)-1表达及Hemin,Znpp干预效果.方法实验分为:(A)正常组,(B)糖尿病组,(C)糖尿病+氯高铁血红素组,(D)糖尿病+锌原卟啉组,观察干预后大鼠血清HO-1活性,含量,肾脏HO-1,Nrf-2的表达,超氧化物歧化酶(SOD),丙二醛(...
糖尿病肾脏疾病血红素加氧酶氧化应激核相关因子2目的观察模拟2型糖尿病大鼠肾脏血红素加氧酶(HO)-1表达及Hemin,Znpp干预效果.方法实验分为:(A)正常组,(B)糖尿病组,(C)糖尿病+氯高铁血红素组,(D)糖尿病+锌原卟啉组,观察干预后大鼠血清HO-1活性,含量,肾脏HO-1,Nrf-2的表达,超氧化物歧化酶(SOD),丙二醛(...