The effects of ziprasidone in rat models were consistent with itsin vitropharmacology and predict clinical antipsychotic efficacy with a low potential for extrapyramidal adverse effects. Ziprasidone therapy does not appear to be associated with sustained elevation of prolactin concentrations. During treatment...
Ziprasidone has not been systematically studied, in animals or humans, for its potential for abuse, tolerance, or physical dependence. While the clinical trials did not reveal any tendency for drug-seeking behavior, these observations were not systematic and it is not possible to predict on the b...
The currently employed aromatase inhibitors have severe side effects whereas our novel aromatase inhibitor is more selective and less toxic, therefore has greater potential to be developed as a drug. The research framework of this study is to identify a potent inhibitor for the aromatase target by ...
However, one potential side effect is that it may change the way the electrical current in your heart works more than some other drugs. The change is small and it is not known whether this will be harmful, but some other drugs that cause this kind of change have in rare cases caused ...
Potential additive effect on QT-interval prolongation (concomitant use contraindicated) when used with drugs that prolong the QT interval. Ziprasidone also is contraindicated in patients receiving drugs shown to cause QT prolongation as an effect and for which this effect is described in the full ...
The decision to switch to ziprasidone in patients with prior suboptimal response has to balance the potential metabolic benefits and the potential relapse risks of the individual patient first and foremost.EBSCO_AspClinical Schizophrenia & Related Psychoses...
While TLC with gas chromatography-mass spectrometry (GC/MS) confirmation cannot exclude all other potential co-ingestions, we feel confident that there were none. The patient's history did not support other ingestions, and the only other agent detected in the urine by TLC and GC/MS was ...
The pharmacodynamic interaction of interest with ziprasidone is its potential to prolong the QTc interval and its combination with other medications that can cause the same cardiac conduction effect. Prolongation of the QTc interval is associated in some drugs with the ability to cause torsades de poi...
However, one potential side effect is that it may change the way the electrical current in your heart works more than some other drugs. The change is small and it is not known whether this will be harmful, but some other drugs that cause this kind of change have in rare cases caused ...
However, one potential side effect is that it may change the way the electrical current in your heart works more than some other drugs. The change is small and it is not known whether this will be harmful, but some other drugs that cause this kind of change have in rare cases caused ...