The active substance in each tablet is 500 mg cefuroxime (present as cefuroxime axetil). The other ingredients are microcrystalline cellulose, croscarmellose sodium type A, sodium lauryl sulphate, hydrogenated vegetable oil, silica colloidal anhydrous, methylhydroxypropyl cellulose, propylene glyco...
ZINNAT tablets containing 250 mg of cefuroxime (as cefuroxime axetil). PHARMACEUTICAL FORM Coated tablet. CLINICAL PARTICULARS Indications ZINNAT is an oral prodrug of the bactericidal cephalosporin antibiotic cefuroxime, which is resistant to most β-lactamases and is active against a wide range of Gra...
Protein binding has been stated as 33 to 50% depending on the methodology used. Following a single dose of cefuroxime axetil 500 mg tablet to 12 healthy volunteers, the apparent volume of distribution was 50 L (CV%=28%). Concentrations of cefuroxime in excess of the minimum inhibitory levels...
Cefuroxime axetil (CAE) was administered orally for five days at either 250 mg twice daily or 500 mg twice daily, to 195 patients aged 14-65 years with mild to moderate skin and soft tissue infections presenting to General Practitioners. It was compared to the standard dose of Augmentin (AUG...