[名词解释] zinc finger motif (锌指结构模序) 相关知识点: 试题来源: 解析 这类蛋白因子往往含有几个相同的指结构,每一个指结构具有以下的保守序列:Cys-X2-4-Cys-Phe-X5-Leu-X2-His-X3-His。这段保守序列中的两个半胱氨酸残基和两个组氨酸残基与锌离子形成配位键,形成环,因此称为锌指,上述具有Cys和...
近观两个金属离子结合位点:一者结合位是为典型的锌指结构(Zinc-finger motif),由四个半胱氨酸(Cysteine)分别为Cys104、Cy… etds.lib.ncku.edu.tw|基于 1 个网页 3. 锌指模式 三、染色质蛋白 ②锌指模式(Zinc-finger motif) ? 如转录因子Ⅲ(TFⅢA)。 ? 这类蛋白在与DNA结合的结构域 由多个有规 … ...
【答案】：锌指基序模体(zinc finger motif)：是真核细胞中，一种序列特异性DNA结合蛋白的结构模体。这种蛋白质含有数个有规律的锌指重复单位，Cys2/His2锌指单位有30个氨基酸残基组成，其中一对半胱氨酸和一对组氨酸与Zn2+形成配位键，每个锌指的C端形成α螺旋负责与DNA结合，蛋白质通过上述锌指单位与...
百度试题 题目锌指模型(zinc finger motif) 相关知识点: 试题来源: 解析 Caspase蛋白酶 反馈 收藏
The zinc-finger motif found in many transcription factors is thought to be important for human heart development and diseases. 在很多转录因子中发现的锌指结构,被认为在人类心脏的发育和相关疾病的发生过程中发挥重要的作用。 www.chinagene.cn 3. Zinc finger nucleases are designed to be like heat-seekin...
There are several types of DNA-binding proteins with azinc finger motif. These proteins have a stretch of about 25 amino acids, about half of which form an α helix, whereas the other half forms two antiparallel β sheets; one of the β sheets together with the α helix holds a zinc at...
锌指结构基元(zinc finger motif) 只看楼主 收藏 回复鳞之趾 四年级 7 这类蛋白因子往往含有几个相同的指结构, 每一个指结构具有以下的保守序列: Cys-X2-4-Cys-Phe-X5-Leu-X2-His-X3-His。这段保守序列中的两个半胱氨酸残基和两个组氨酸残基与锌离子形成配位键, 形成环, 因此称为锌指, 上述具有...
1) zinc finger motif 锌指基序1. Based on the genome database, the cloning was used strategy of the novel gene which is the homologous gene of a specific gene,and the human novel gene TFL 76 was obtained, which encoded 12 C 2H 2 zinc finger motifs. 运用基于基因组数据库特定基因同源...
The short sequence motif named 'zinc finger', first recognized repeated in tandem in the Xenopus transcription factor IIIA (TFIIIA) 1,2 , is also found in the yeast transcriptional activator SWI5 (ref. 3) and many other regulator proteins 4 . Embedded in the 709-amino-acid polypeptide chain...
Implications of the zinc-finger motif found in the DNA-binding domain of the human XPA protein. Genes Cells. 1996 May;1:437-42.Morikawa K, Morita EH, Ohkubo T, Kuraka T, Shirakawa M, and Tanaka K. Implications of the zinc-finger motif found in the DNA-binding domain of the human ...