Zinc-finger proteins (ZNFs) are one of the most abundant groups of proteins and have a wide range of molecular functions. Given the wide variety of zinc-finger domains, ZNFs are able to interact with DNA, RNA, PAR (poly-ADP-ribose) and other proteins. Thus, ZNFs are involved in the...
Zinc finger proteins: watchdogs in muscle development. Mol Gen Genet 1999; 261: 209-15Krempler A, Brenig B. Zinc finger proteins: watchdogs in muscle development. Mol Gen Genet. 1999; 261 :209–215. doi: 10.1007/s004380050959. [ Cross Ref ]...
Arabidopsis BIRD Zinc Finger Proteins Jointly Stabilize Tissue Boundaries by Confining the Cell Fate Regulator SHORT-ROOT.pdf 2015-05-15上传 暂无简介 文档格式: .pdf 文档大小: 3.18M 文档页数: 16页 顶/踩数: 0/0 收藏人数: 0 评论次数:
Zinc Finger Proteins Zinc finger (ZnF) proteins are a massive, diverse family of proteins that serve a wide variety of biological functions. Due to their diversity, it is difficult to come up with a simple definition of what unites all ZnF proteins; however, the most common approach is to ...
The uteroglobin (UG) gene family encodes a fascinating group of secreted proteins that includes rat prostatic steroid-binding protein subunit C3, human Clara cell 10-kDa protein, human mammaglobin, and rabbit UG. In the rabbit, UG is a progesterone-dependent preimplantation uterine protein with pea...
Proteins containing the zinc finger domain(s) are named zinc finger proteins (ZFPs), one of the largest classes of transcription factors in eukaryotic genomes. A large number of ZFPs have been studied and many of them were found to be involved in regulating normal growth and development of ...
One of the best known proteins of this family is a well conserved protein known as CTCF, which plays a key role in the establishment of the chromosomal architecture in vertebrates. The distinctive features of C2H2 zinc finger proteins include strong and specific binding to a long and unique ...
Zinc-finger proteins (ZFPs) that recognize novel DNA sequences are the basis of a powerful technology platform with many uses in drug discovery and therapeutics. These proteins have been used as the DNA-binding domains of novel transcription factors (ZFP TFs), which are useful for validating ge...
Zinc-finger nucleases are hybrid proteins consisting of polymeric zinc-finger proteins fused to the endonuclease domain of the restriction enzyme Fok I. A pair of zinc-finger nucleases binds to two contiguous target sequences in each DNA strand separated by a 6 bp cleavage site. Subsequent ...
c2h2 型锌指对生物大分子的识别c2h2 zinc-finger - 药学学报.pdf,834 药学学报 Acta Pharmaceutica Sinica 20 13, 48 (6): 834 84 1 C2H2 型锌指对生物大分子的识别 多* ( 中国医学科学院、北京协和医学院药物研究所, 天然药物活性物质与功能国家重点实验室, 北京 100050)