11, 12, 13 They can also chelate divalent heavy metals such as cadmium, lead, mercury or platinum via the thiol groups of cysteine residues and thus help to cell detoxification and protection.14 MTs overexpression has been linked to chemoresistance in carcinoma cells,15 non-small cell lung ...
The zinc-eugenolate matrix chelate is very unstable in water. Its hydrolysis forms eugenol and zinc hydroxide, releasing the zinc oxide particles exposed in the process. In vitro studies showed that zinc 2-ethoxybenzoate matrix formed in EBA-eugenol cements is even more prone to hydrolysis than ...
3). Specifically, we observed the loss of signal corresponding to the two OH groups and the NH proton in Ybt, which indicates the corresponding heteroatoms that chelate the Zn2+ ion. Although the other zinc-coordinating atoms were not directly characterized, we hypothesize that Ybt binds zinc ...
autophagy or necrosis4,5. Ferroptosis is an iron-dependent accumulation of lipid reactive oxygen species (ROS) process. Small molecule inducers or inhibitors of ferroptosis through targeting iron metabolism or lipid peroxidation have been extensively...
Yellow Stripe-Like (YSL) proteins are involved in the uptake and transport of metal ions. They play important roles in maintaining the zinc and iron homeostasis in Arabidopsis, rice (Oryza sativa), and barley (Hordeum vulgare). However, proteins in this
These changes may be related to the dose of Zn added, given the prior descriptions that supplementation with 50 mg/kg chitosan Zn chelate had no differential effect on apoptosis compared to 100 mg/kg ZnSO4, which significantly reduced ileal apoptosis and increased the ratio of villi height to ...
while a zinc amino acid chelate raised plasma zinc in all subjects tested. In addition, in a rat supplementation study, neither zinc gluconate nor zinc sulfate was as effective as a zinc–amino acid chelate in protecting against chemically induced oxidant damage. Thus, zinc gluconate seems to be...
dissolving casein, zinc ash, chelate zinc content is high, and a high viscosity, having good emulsifying, while solves the prior art using materials dissolved, acid precipitation, rubber grinding, transformation, such as spray drying process is complicated manual labor and energy consumption issues. ...
The zinc complex of 3,5-di-tert-butyl salicylate (Zn{[CH3)3C]2Sal}22−) is a zinc ion chelate of salicylate. In this study, we found that this compound inhibits viability, invasion, and migration and induces apoptosis in triple-negative breast cancer 4T1 cells. RNA-seq showed that th...
2h–j), because Chelex-100 (CX), which was used to create zinc deficiency in fetal calf serum (FCS) (see Methods), causes deficiency of zinc and also several other trace elements, as it can chelate divalent cations. Fig. 2 Marked reduction of ENPP1, ENPP3, and NT5E/CD73 activities...