ZnT and Zip are known to decrease and increase cytosolic zinc concentrations respectively. Both zinc transporters are suggested to be implicated in a number of disorders and disease states through dysfunctional zinc transport including cancer, diabetes and gastrointestinal ( GI) disease.Myers, Stephen...
Rotavirus is a common virus that causes gastrointestinal diseases. It has great clinical harm, wide distribution and high infectivity. It is mainly transmitted through fecal mouth and can infect small intestinal epithelial cells, cause cell damage and cause diarrhea. After infantile infection with rotav...
children are 3 to 5 times the adult requirement, and the diet can usually supply the required amount. If the intake is insufficient, absorption and utilization or excretion is lost too much, zinc deficiency can occur, manifested in skin, gastrointestinal, endocrine, neuropsychiatric...
However, excessive zinc intake can lead to adverse effects, such as gastrointestinal upset, nausea, vomiting and impaired copper absorption. Zinc supplements are usually taken by populations that are demonstrated to need extra zinc outside their daily diets. These populations include:Babies older ...
Lead is absorbed in the gastrointestinal tract; it is retained by soft tissues and stored in bone. • Lead is slowly excreted by the kidneys and appears to affect major organs, as seen in direct effects of necrosis in gastrointestinal tract epithelium, damage to red blood cells (increased fr...
Single doses of 225 to 450 mg of zinc usually induce vomiting. Milder gastrointestinal distress has been reported at doses of 50 to 150 mg/day of supplemental zinc. (33) One major consequence of long-term consumption of excessive zinc is copper deficiency. Total zinc intakes of 60 mg/day...
gastrointestinal bleeding, some drugs, or metabolic acidosis (for which baking soda is helpful), could lead toHyperkalemia(elevated blood potassium). However even in healthy individuals, supplementing too much potassium may affect the balance of other electrolytes such as magnesium, sodium, chloride.....
Arthur B.Atlas,Joel R.Rosh, inPediatric Gastrointestinal and Liver Disease (Fourth Edition), 2011 Trace Metals Normalzinc metabolismis critical for normal growth and immune function. Approximately 30% of young infants diagnosed with CF by newborn screening have been shown to have low plasma zinc ...
gastrointestinal hormone secretion. Relevant clinical research results show that zinc supplementation (zinc aspartate, zinc taurate, zinc glutamate) treatment can help accelerate the relief of clinical symptoms in children with diarrhea, shorten the treatment process, and promote the recovery of normal ...
Normally, nausea and vomiting are accompanied by stomach pain and diarrhea. Gut discomfort and gastrointestinal bleeding have also been observed, however, these are less prevalent. A patient who took an overdose of220 mg of zinc sulfatetwice daily for acne therapy developed intestinal hemorrhage in ...