Haraa H,Hayashi K,Aoyama Y.Intestinal absorption of zinc is promoted by low-level intake but inhibited by high-level intake of corn husk fiber in rats. Nutrition Research . 2001Intestinal absorption of zinc is promoted by low-level intake but inhibited by high-level intake of corn husk ...
Combining site-directed mutagenesis, metal binding affinity assays, and X-ray absorption spectroscopy demonstrated how two Zn2+ ions bind sequentially to two different sites in the cytosolic loop due to different zinc affinities [98]. First, one Z n2+ ion binds to a CysHis3 site with...
The absorption of Zn2+by mammals mostly occurs in the distal small intestine, and the absorption process is mainly divided into four stages: intestinal cell uptake, mucosal cell transport, portal vein circulation, and endogenous zinc secreted back to intestinal cells [48]. Intestinal cells regulate...
With respect to dietary composition, zinc supplementation as part of a meal can significantly reduce zinc absorption when compared to water-based solutions of zinc (164). Moreover, dietary phytate, a natural chelator of zinc ions that is present in corn, rice, and cereals, can severely ...
Because the rs12979860 CC genotype has been shown to mediate higher hepatic IFN-l3 expression53–55, we hypothesized that elevated serum IFN-l3 could drive zinc absorption across the intestinal epithelium; an effect observed during endotoxemia56. To examine the movement of zinc across a monolayer ...
used the double-isotope tracer method with 67Zn and 70Zn, and found that the median (IQR) fractional absorption of zinc from zinc oxide (49.9%) was significantly lower than that from zinc citrate (61.3%) and zinc gluconate (60.9%), but there was no marked difference between two organic ...
[45]Siebert F, Lühken G, Pallauf J, Erhardt G (2012) Mutation in porcine Zip4-like zinc transporter is associated with pancreatic zinc concentration and apparent zinc absorption. Br J Nutr 109: 969–76. doi: 10.1017/s0007114512002772 ...
1. Zinc is taken up into human red cells by two mechanisms that depend upon the presence of anions. One of these requires bicarbonate ions, is inhibited by... V Kalfakakou,TJ Simons - 《Journal of Physiology》 被引量: 130发表: 1990年 Dietary zinc absorption: A play of Zips and ZnTs...
Zinc is known to be indispensable to growth and development and transmission of the genetic message. It does this through a remarkable mosaic of zinc binding motifs that orchestrate all aspects of metabolism. There are now nearly 200 three dimensional st
Garcia-Iniguez L, Powers L, Chance B, Sellin S, Mannervik B, Mildvan AS. 1984 X-ray absorption studies of the Zn2+site of glyoxalase I.Biochemistry23, 685-689. Google Scholar Garcia-Saez I, Reverter D, Vendrell J, Aviles FX, Coll M. 1997 The three-dimensional structure of human ...