Zika virus (ZIKV) is a Flavivirus spread by infected Aedes mosquitoes. Although the virus has been known since 1947, it hit the headlines in 2015 with major outbreaks in Brazil and other Latin American countries as well as the Caribbean. Cases of microcephaly, in which babies are born with...
Zika virus (ZIKV), a mosquito-borne flavivirus, was first identified in the 1940s in Uganda in Africa and emerged in the Americas in Brazil in May 2015. In the 30 months since ZIKV emerged as a major public health problem, spectacular progress has been made with vaccine development cumulat...
Zika virus (ZIKV), a mosquito-borne flavivirus, was first identified in the 1940s in Uganda in Africa and emerged in the Americas in Brazil in May 2015. In the 30 months since ZIKV emerged as a major public health problem, spectacular progress has been m
Zika virus (ZIKV) is an emerging arbovirus that causes a mosquito-borne disease. Although infection with ZIKV generally leads to mild disease, its recent e
Zika virus has largely disappeared from the Americas. No additional countries have reported active local transmission of Zika since late 2016, according to the Pan American Health Organization. Provisional data from the CDC show that in 2017, 424 cases o
Zika virus (ZIKV) is a mosquito-borne virus that has a high risk of inducing Guillain–Barré syndrome and microcephaly in newborns. Because vaccination is considered the most effective strategy against ZIKV infection, we designed a recombinant vaccine utilizing the baculovirus expression system with ...
Zika virus vaccines: immune response, current status, and future challenges Curr. Opin. Immunol. (2018) V. Cimica et al. Adjuvant formulations for virus-like particle (VLP) based vaccines Clin. Immunol. (2017) M. Tan et al. Subviral particle as vaccine and vaccine platform Current opinion...
Zika virus(ZIKV) is rapidly spreading across the America and its devastating outcomes for pregnant women and infants have driven this previously ignored pathogen into the limelight.Clinical manifestations are fever,joint pain or rash and conjunctivitis.Emergence of ZIKV started with a first outbrcak ...
2a). No ZIKV RNA or infectious virus were detected in uninfected control animals at any point throughout the study. At day 14 post-infection, a decrease in testicle size (Fig. 1b and Supplementary Fig. 2b) and weight (Fig. 1c) were observed in several of the infected mice, which ...
Flavivirus Transmission Urban Sylvatic 1. Introduction The history of Zika virus, from the first isolation from a sentinel monkey exposed in the Zika Forest near Entebbe, Uganda in 1947 to its current status as a public health emergency of international concern has been comprehensively reviewed elsew...