This gene encodes a transcription factor with multiple homeodomains and zinc finger motifs, and regulates myogenic and neuronal differentiation. The encoded protein suppresses expression of the alpha-fetoprotein gene by binding to an AT-rich enhancer motif. The protein has also been shown to negatively...
Multiple transcript variants expressed from alternate promoters and encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009] 基因名: ZFHX3 别名: ATBT,ATBF1,ZFH-3,ZNF927,C16orf47 基因ID: 463 Chromosome:(GRCh37) 16 Start: 72816784 End: 73092534 Strand: 信号...
This gene encodes a transcription factor with multiple homeodomains and zinc finger motifs, and regulates myogenic and neuronal differentiation. The encoded protein suppresses expression of the alpha-fetoprotein gene by binding to an AT-rich enhancer motif. The protein has also been shown to negatively...
提供的ZFHX3人源重组蛋白(Q01)产品为带有GST标签的人源ZFHX3部分序列重组蛋白,其对应的GeneID号为463。 产品描述 与其它公司提供的重组蛋白不同,该ZFHX3人源重组蛋白(Q01)产品为采用CFS的无细胞麦胚蛋白合成系统表达出来的重组蛋白,可表达出对细胞有毒性、易被蛋白酶降解的蛋白;并获得具有良好的可溶性,并有翻译...
Multiple transcript variants expressed from alternate promoters and encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009] [中文简述(自动翻译):] 该基??因编码具有多个homeodomains和锌指结构的转录因子,并调节肌和神经元分化。所编码的蛋白质通过结合到一个富含AT的增强...
Atrial fibrillationCerebral infarctionLung thromboembolismSingle nucleotide polymorphismWe aimed to study a single nucleotide polymorphism (SNP), rs2106261, in the transcription factor gene, ZFHX3, in atrial fibrillation (AF) and other related phenotypes by phenome scanning in a Japanese population....
This gene encodes a transcription factor with multiple homeodomains and zinc finger motifs, and regulates myogenic and neuronal differentiation. The encoded protein suppresses expression of the alpha-fetoprotein gene by binding to an AT-rich enhancer motif. The protein has also been shown to negatively...
(ZFHX3) transcription factors functionally interact in the regulation of genes in HCC cells. Here, we report that hypoxia increases the transcription of the ZFHX3 gene and enhances the binding of HIF1A to the ZFHX3 ...
The ATBF1/ZFHX3 gene at 16q22 is the second most frequently mutated gene in human prostate cancer and has reduced expression or mislocalization in several types of human tumors. Nonetheless, the hypothesis that ATBF1 has a tumor suppressor function in prostate cancer has not been tested. In ...
A zinc finger homeobox 3 (ZFHX3, also named AT-motif binding factor 1, ATBF1) gene variant has been found in patients with AF. However, the ... Q Jiang,B Ni,J Shi,... - 《Biochemical & Biophysical Research Communications》 被引量: 37发表: 2014年 Additive Effect of Zfhx3/Atbf1 ...