中文名称: 化合物 ZED-1227 英文名称: ZED-1227 CAS号: 1542132-88-6 品牌: TargetMol 产地: 美国 保存条件: store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. 纯度规格: 99.04% 产品...
ZED-1227 纯度: 99.04% 产品编号 T17289 别名ZED-101, TAK-227Cas号 1542132-88-6 ZED-1227 (TAK-227) 是一种具有口服活性、选择性和高效性的转谷氨酰胺酶 2 (TG2) 抑制剂,具有抗癌活性,能阻塞炎症诱导的 TG2 表达和激活,可用于治疗乳糜泻。
ZED-1227 CAS号: 1542132-88-6 英文名: ZED-1227 英文别名: ZED-1227;ZED 1227,ZED1227;Methyl (S,E)-7-((1-(2-((2-ethylbutyl)amino)-2-oxoethyl)-2-oxo-1,2-dihydropyridin-3-yl)amino)-6-(1-methyl-1H-imidazole-5-carboxamido)-7-oxohept-2-enoate;2-Heptenoic acid, 7-[[1-[2...
ZED-1227 是一种特异性的,具有口服活性的转谷氨酰胺酶 2 (TG2) 抑制剂,IC50值为 45 nM。ZED-1227 能阻塞炎症诱导的 TG2 表达和激活,可用于乳糜泻的研究。 详细介绍 产品活性:ZED-1227 是一种特异性的,具有口服活性的转谷氨酰胺酶 2 (TG2) 抑制剂,IC50值为 45 nM。ZED-1227 能阻塞炎症诱导的 TG2...
ZED-1227,来源于药化词典-药智数据
Specification/PurityPackingUnit Price(USD)StockQuantityShopping Cart 98%+10mg$0.00100 98%+25mg$0.00100 98%+50mg$0.00100 98%+100mg$0.00100 Online ConsultationShopping Cart Product safety Specification HF05141 ZED1227 Product Details Analogs can be customized for you. ...
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Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemEZED-1227Cat. No.: HY-19359CAS No.: 1542132-88-6分式: CHNO分量: 528.6作靶点: Glutaminase作通路: Metabolic Enzyme/Protease储存式: Please store the product under the recommended conditions inthe COA.BIOLOGICAL ACTIVITY物活性 ZED...
November 2021 © Der/die Autor(en) 2021 Ron Fried Klinik für Gastroenterologie und Hepatologie, Universitätsspital Zürich, Zürich, Schweiz ZED1227 – vielversprechende medikamentöse Therapie der Zöliakie? Originalpublikation Schuppan D, Mäki M, Lundin KEA et al (2021) A Randomized...
Therefore, the development program of less electrophilic Michael-acceptor class molecules as transglutaminase inhibitors was initiated by our group, eventually leading to the discovery of ZED1227, becoming the first clinical stage TG2 inhibitor. In an initial gluten challenge study, ZED1227 was shown ...