if(is.numeric(scale )) attr(x,'scaled:scale') <- scale 那么默认参数下,我们就是对矩阵按列进行z-score的标准化。检验标准很简单,计算标准化的数据的均值和标准差,因为z-score的结果就是让数据服从均值为0,标准差为1的正态分布。 > mean(y) 0 > sd(y) 1 这解决了我多年的疑惑,为啥我在R语言中...
之所以说Z-score并不会影响很多统计学算法,是因为Z-score只改变了数据的量级并**未改变数据的分布,**比如,以降维为主的PCA分析: 代码语言:javascript 复制 library(FactoMineR)#画主成分分析图需要加载这两个包library(factoextra)x1<-PCA(x,graph=FALSE)pca_x<-fviz_pca_ind(x1,geom.ind="point",addEllipses...
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(top 1% empirical distribution of CMS score = 12.831). The genome region harboring the geneLCAT(lecithin-cholesterol acyltransferase) is marked in this figure.BHaplotype network based on the SNPs in theLCATregion (ChrZ:24,935,941–24,982,741). Each circle represents a haplotype, and its...
{ "attackComplexity": "HIGH", "attackVector": "LOCAL", "availabilityImpact": "NONE", "baseScore": 6.3, "baseSeverity": "MEDIUM", "confidentialityImpact": "HIGH", "integrityImpact": "HIGH", "privilegesRequired": "NONE", "scope": "UNCHANGED", "userInteraction": "REQUIRED", "vector...
Red (positive ISM score) indicates that substitution of the original nucleotide leads to a decreased average Z-DNA score across the stretch of the (CA)n repeat; Blue (negative ISM score) indicates the other way. e, Boxplot showing the distribution of ISM scores at various positions near the...
H2A.Z positive and H2A.Z negative promoters. The heatmap is sorted by MNase-seq signal in Ctrl embryos. Tracks show the signal obtained after merging two biological replicates per condition.bProfile plots of insulation score in Zld-dependent, H2A.Z positive and H2A.Z negative promoters comparing...
AIRE is an unconventional transcription factor that enhances the expression of thousands of genes in medullary thymic epithelial cells and promotes clonal deletion or phenotypic diversion of self-reactive T cells1,2,3,4. The biological logic of AIRE’s target specificity remains largely unclear as, ...
if(is.numeric(scale )) attr(x,'scaled:scale') <- scale 那么默认参数下,我们就是对矩阵按列进行z-score的标准化。检验标准很简单,计算标准化的数据的均值和标准差,因为z-score的结果就是让数据服从均值为0,标准差为1的正态分布。 > mean(y) 0 > sd(y) 1 这解决了我多年的疑惑,为啥我在R语言中...