NF-kappa BProstatic Neoplasms腺癌抗原CD95脱噬作用Many tumors are resistant to Fas ligand (FasL)-induced apoptosis. This study examined the role of tumor-derived TNF-alpha, via an autocrine/paracrine loop, in the regulation of tumor-cell resistance to FasL-induced apoptosis. We have reported ...
Induction of RKIP expression inhibits the activation of signal transducer and activator of transcription 3 (STAT3), NF-[kappa]B pathway, and downstream Yin Yang 1 (YY1) as well as antiapoptotic gene products, causing induction of apoptosis in breast and prostate cancer cells [85-87]. Molecular...
GSEA of the NF-kappa B/Snail/YY1/RKIP circuitry in multiple myeloma The objective of this study was to analyze the expression profile of the angiogenic components, vascular endothelial growth factor-A (VEGFA), basic fibrobl... A Zaravinos,P Kanellou,GI Lambrou,... - 《International Journal...
NF-κ B Regulation of YY1 Inhibits Skeletal Myogenesis through Transcriptional Silencing of Myofibrillar Genes. Carathers M, Davuluri R, Guttridge DC (2007) NF-kappaB regulation of YY1 inhibits skeletal myogenesis through transcriptional silencing of myofibrillar genes... Huating,Wang,Hertlein,... - ...
Mechanistically, nuclear factor kappa B (NF-κB) and Yin Yang 1 (YY1) directly bound to the LINC01578 promoter, enhanced its activity, and activated LINC01578 expression. LINC01578 was shown to be a chromatin-bound lncRNA, which directly bound NFKBIB promoter. Furthermore, LINC01578 interacted...
NF-κ B signaling is implicated as an important regulator of skeletal muscle homeostasis, but the mechanisms by which this transcription factor contributes to muscle maturation and turnover remain unclear. To gain insight into these mechanisms, gene expression profiling was examined in C2C12 myoblasts ...
NFKB: nuclear factor kappa B ME: microenvironment References ,90(13), 6145–6149. Lee, J. S., Galvin, K. M., See, R. H., Eckner, R., Livingston, D., Moran, E., & Shi, Y. (1995). Relief of YY1 transcriptional repression by adenovirus E1A is mediated by E1A-associated prot...
We found that (1) chronic oxidative stress is a potent inducer of S100B expression via NF-κB activation; (2) upregulated S100B causes myoblasts to convert into brown adipocytes via an NF-κB/YY1 axis that negatively regulates the promyogenic and anti-adipogenic miR-133 with consequent ...
Ref-1 reduces cysteine residues of various transcription factors that are crucial to B-cell activation during TI responses, including AP-1, NF-κB, and BSAP, and enhances their activity (Tell et al., 2000; Xanthoudakis and Curran, 1992; Xanthoudakis et al., 1992). What is finally...
vascular endothelial growth factor and nuclear factor kappa- light-chain-enhancer of activated B cells, which promote tumor immunity, inflammation and angiogenesis.6–8 p53 has a controversial role in ROS formation.9 ROS trigger p53 activation to regulate target genes and mediate p53-dependent apoptos...