Culturing these myoblasts in media containing 2% human serum to study their fusion and differentiation also resulted in no difference between young and old serum conditions in terms of the percentage of nuclei inside myosin heavy chain positive myotubes. Despite the variability of different samples of...
Pannexin 1 modulates angiogenic activities of human endothelial colony-forming cells through IGF-1 mechanism and is a marker of senescence BACKGROUND We examined the role of pannexins in human endothelial progenitor cell (EPC) senescence. METHODS Young and replication-induced senescent endothe... T ...
Two children and one young adult with extremity sarcomas demonstrating an aggressive clinical behavior are described. Histologically, all three tumors disp... W.M.,Molenaar,and,... - 《Human Pathology》 被引量: 86发表: 1989年 Atypical teratoid/rhabdoid tumor of the spine in an adult: case re...
However, recent data strongly indicate that VDR is expressed in C2C12 myoblasts and myotubes [16, 17], in murine skeletal muscle [18], and in situ detection of VDR in human skeletal muscle points towards a role of vitamin-D on muscle function [19, 20]. In addition, VDR has been ...
To test the possibility of the involvement of the caspases in SC death in human ageing muscle, we analysed both the initiator caspases, namely, caspase-8 and caspase-9, and the effector caspases, namely, caspase-3, in the absence and presence of specific or broad pharmacologic inhibitors. ...
2.1. Human dental pulp stem cells obtention Intact third molars were collected from young men and women (aged from 15 to 35 years old). All patients read and signed the informed consent and agreed to participate in donating the extracted tooth, which was always extracted for reasons independent...
et al. Primary human muscle precursor cells obtained from young and old donors produce similar proliferative, differentiation and senescent profiles in culture. ageing cell. 12, 333-344 (2013).Alsharidah M, Lazarus NR, George TE, Agley CC, Velloso CP, Harridge SD. Primary human muscle ...