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Isolated metabolites of (1R-trans)-N-[[2-(2,3-dihydro-4-benzofuranyl)cyclopropyl]-methyl]propanamide, methods for their use, and compositions containing the metabolites.ドレスマン, マリーン, ミシェルファドケ, ディーパック
The novel 4-(7-bromo-5-methoxy-2-benzofuranyl)piperidine of the formula is prepared by solvolysis of derivatives thereof which contain on the nitrogen atom an appropriate group which can be replaced by hydrogen. The compound of the formula I can be converted into its acid addition salts. ...
Their use as a new indanyl oxy dihydrobenzofuranyl acetic acid derivatives and GPR40 receptor agonistThe present invention has valuable pharmacological properties, in particular binds to the GPR40 receptor, modulating its activity, the general formula I the radicals R R and m are as described in...