The EPHA3 protein tyrosine kinase, a member of the ephrin receptor family, regulates cell fate, cell motility, and cell–cell interaction. These cellular events are critical for tissue development, immunological responses, and the processes of tumorigene
Consistently, TEAD depletion had little effect on IL6 promoter activity and YAP enrichment at MaSC signature-gene promoters (Supplementary Fig. 8d,e). Collectively, these data suggest that SRF is the critical transcription factor responsible for YAP induction of MaSC signature-gene expression and ...