The sedating effects of xylazine, which can last for hours, may also put individuals at greater risk for victimization or injury from assault or exposure to the elements [10]. In addition to its sedating properties, xylazine can also cause severe skin ulcers in humans, regardless of route ...
Avoid accidental administration to humans. Should such exposure occur, notify a physician immediately. Artificial respiration may be indicated. InCervidae, occasional capture-associated deaths occur. Clinical trials reveal a mortality rate of approximately 3.5% attendant with the administration of xylazine....
More importantly, they advocate for research on xyla- zine and its effect on humans because: "it is a veterinary drug and is not approved for human use. [...] Unfortu- nately, its use in humans can be fatal, especially in over- dose cases." (p.498) Xylazine was confirmed...
Effects on the Heart In rabbits, the combination of ketamine with xylazine (9.4–38.9 mg) suppressed tachyarrhythmias at a high dose of>399 mg/kg [189]. As an anaesthetic, ketamine is often hailed as a good agent for short-term surgery in both humans and animals, because the patients rec...
These similar pharmacologic effects may create synergistic toxic effects in humans. Therefore, fatalities among drug users may increase due to the use of xylazine hydrochloride as an adulterant. Xylazine hydrochloride alone has proven harmful to humans and even more when it is combined with drugs ...
reliever. According to FDA, “it is not safe for use in humans and may result in serious and life-threatening side effects that appear to be similar to those commonly associated with opioid use, making it difficult to distinguish opioid overdoses from xylazine exposure.” Xylazine can increase...