Human - woman DOSE/DURATION : 8 mg/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Behavioral - changes in motor activity (specific assay) Cardiac - pulse rate REFERENCE : CTOXAO Clinical Toxicology. (New York, NY) V.1-18, 1968-81. For publisher information, see ...
Because human xylazine use has been reported in other locations outside of Puerto Rico, this substance could also emerge as an adulterant in other markets to the levels currently experienced in Puerto Rico. Research and interventions are needed to provide adequate services on the island...
The prevalence of xylazine, a non-opioid tranquilizer not for human consumption, in illicitly manufactured fentanyl is increasing in the United States. However, little is known about xylazine awareness and attitudes among people who use drugs. A cross-se
In the human, there are also data available on the effects of ketamine on the heart: Jakobsen et al. [205]. reported that even a small dose of 0.5 mg/kg ketamine reduced left ventricular systolic and diastolic functions in patients with ischaemic heart, whilst a single dose of 1 mg/kg ...
NOT FOR HUMAN USE KEEP OUT OF REACH OF CHILDREN REFERENCES 1. Detweiler, D.K.: “The Diagnosis and Significance of Cardiac Arrhythmias.”Progress in Equine Practice. Edited by E.J. Catcott and J.F. Smithcors. American Veterinary Publications, Inc., Santa Barbara, California and Wheaton, Il...
agent in 1962 by Farbenfabriken Bayer in Leverkusen, Germany. Accounts of the actions and uses of xylazine in animals were reported as early as the late 1960s and early 1970s. Results from early human clinical studies confirmed that xylazine has several central nervous system depressant effects....
Xylazine is marketed as a veterinary drug and used for sedative and analgesic purposes; it is not approved for human use due to various side effects. In recent years, xylazine has emerged as a drug of abuse and has been associated with drug-facilitated sexual assaults. Herein, we describe,...
CAS No. : 7361-61-7 Name : Xylazine Biological Activity Description:Xylazine is α2 class of adrenergic receptor agonist.Target: Adrenergic ReceptorXylazine is a drug that is used for sedation, anesthesia, muscle relaxation, and analgesia in animals such as horses, cattle and other non-human ma...
Xylazineis a sedative drug used in veterinary medicine. It is not approved or intended for human consumption.Some drug usersintentionally consume xylazine in combination with drugs of abuse, such as illicit fentanyl, to strengthen its effects, while other users are unaware that xylazine is sometimes...
Xylazine is marketed as a veterinary drug and used for sedative and analgesic purposes; it is not approved for human use due to various side effects. In recent years, xylazine has emerged as a drug of abuse and has been associated with drug-facilitated sexual assaults. Herein, we describe,...