Dosing informationUsual Adult Dose for Influenza:20 kg to less than 80 kg: 40 mg orally once as a single dose At least 80 kg: 80 mg orally once as a single dose Use: -For the treatment of acute uncomplicated influenza in patients symptomatic for no more than 48 hours who are otherwise...
Single-dose Xofluza is the first and only antiviral medicine indicated specifically for patients at high risk of developing serious complications from influenza (flu) The Centers for Disease Control and Prevention (CDC) defi...
Xofluza (baloxavir) is commonly used for the treatment of the flu (influenza A and B), but only within the first two days of having flu symptoms. Xofluza is also used for the prevention of flu. The flu, short for influenza, is caused by influenza viruses that infect parts of the ...
Important Dosing Information Instruct patients to begin treatment with XOFLUZA as soon as possible at the first appearance of influenza symptoms, within 48 hours of onset of symptoms. Instruct patients to start taking XOFLUZA for prevention as soon as possible after exposure [see DOSAGE AND ADMINI...
Xofluza is also "simpler to take -- just one tablet, compared with other options, one of which requires twice daily dosing for 5 days," Glatter said. The drug's approval was based on two clinical trials of more than 1,800 patients who took either Xofluza, a placebo or another antiv...
Participants enrolled in the study were recruited in parallel into two cohorts: children aged five to less than 12 years and children aged one to less than five years. Participants were randomly assigned to receive a single-dose of ...
important first line of defence in preventing the flu, there is a need for new medical options for prophylaxis and treatment. Current antiviral drugs have limitations with respect to efficacy, convenience of dosing, and resistance. Roche is committed to addressing the unmet need in th...
as a result of comparing Xofluza and placebo in various family members (adults and children) in the BLACKSTONE study, Xofluza reduced the risk of influenza infection after exposure to infected family members by 86 percent more than the placebo, demonstrating statistically significant prevention effec...
12.2 Pharmacodynamics Cardiac Electrophysiology At twice the expected exposure from recommended dosing, XOFLUZA did not prolong the QTc interval. Exposure-Response Relationships In patients 5 years of age and older, when XOFLUZA is dosed by weight as recommended, a flat baloxavir exposure-response ...
Although vaccines are an important first line of defense in preventing the flu, there is a need for new medical options for prophylaxis and treatment. Other antiviral medicines have limitations with respect to efficacy, convenience ...