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Both inhibition of ERK2 activation, which decreased Bcl-xl synthesis, and downregulation of Bcl-x by antisense oligonucleotide treatment inhibited the survival-promoting activity of FGF2. Thus, FGF2-induced cell survival is a progressive adaptive phenomenon involving ERK2 activation by excreted FGF1 ...
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Product Name: XFGF-20 protein Synonyms: XFGF-20 protein CAS: MF: MW: 0 EINECS: Mol File: Mol File Information Error Report Your Email: Browse by province XFGF-20 protein Suppliers Global suppliers XFGF-20 protein Recommend Suppliers Recommend You Select Member Companies 1 Tag: X...
Fibroblast growth factor (FGF) signaling mediates cell-to-cell communication in development and organ homeostasis in adults. Of the four FGF receptor (FGFR... Huang,X. - 《Cancer Research》 被引量: 188发表: 2006年 FGF18 in colorectal tumour cells: autocrine and paracrine effects Fibroblast grow...
Specifically in zebrafish embryos, Fgf signaling plays a role in morphogenesis and cell fate determination of myotomes [17], and is required for fast muscle differentiation [18]. Furthermore, it has been shown that Fgfs promote satellite cell proliferation [19], [20], [21] and, therefore, ...
We report here the autosomal location of WT1, SF1, LHX1, LHX9, FGF9, WNT4 and RSPO1 in platypus, thus excluding these from being key regulators of sex determination in this species. We found that GATA4 maps to sex chromosomes Y1 and X2; however, it lies in the pairing region shown...
After 24 h of FGF exposure, SHH is upregulated 2.1-fold around the FGF bead. This correlated with RT-qPCR data (upregulated 5.5-fold) (Figure 3C). Genes associated with SHH expression include the distally restricted HOXA13, HOXD13, and LHX2. Other upregulated SHH-associated genes include...