The delivery of drug substance through the mucosa (oral) presents a great opportunity but also poses continuing challenges. Xerostomia, the excessive dryness of mouth, and reduction in the saliva secretion poses a debilitating condition for majority of patients. Evaluation of xerostomia starts with ...
Thus, despite significant improvements in RT planning and delivery introduced during the last number of decades, the need for effective alleviation of dry mouth syndrome is still present in a substantial proportion of HNC patients. Pilocarpine Pilocarpine is a nonselective cholinergic parasympathomimetic ...
Xerostomia, or dry mouth, is a very common symptom amongst the terminally ill and can have profound negative effects on patients' quality of life. Yet, it is often considered trivial and therefore tends to be neglected and ignored. This review examines the pathophysiology, aetiology and methods...
Xerostomia, commonly known as dry mouth, is a distressing condition characterized by a patient’s subjective sense of a reduced or absent saliva flow [1]. Xerostomia could be clinically accompanied by hyposalivation, also called salivary gland hypofunction [2]. It can result from various etiolo...
Physical examination is focused on the oral cavity, specifically any apparent dryness (eg, whether the mucosa is dry, sticky, or moist; whether saliva is foamy, thick, stringy, or normal in appearance), the presence of any lesions caused by Candida albicans, and the condition of the teeth....
Conclusion Zishen Shengjin Buccal Tablet might have significant short effect on the level of mouth dryness of maintenance hemodialysis patients with xerostomia,while it might have little effect on patients' dialysis dehydration volume. 展开 被引量: 1 ...
correlated with the quantitative results of salivary production. At the 15 mg and 20 mg doses, statistically significant differences compared to placebo were demonstrated in a variety of domains including items that rated improvement in speak...
NOTES OF A CASE OF XEROSTOMIA (MOUTHDRYNESS).NOTES OF A CASE OF XEROSTOMIA (MOUTHDRYNESS).. By - ArthurJ. Sharp M.D. LOND., F.R.C.S. ENG.doi:10.1016/S0140-6736(01)77363-1SharpArthurJ.Elsevier Ltd.Lancet
Carpenter PA, Schubert MM, Flowers ME (2006) Cevimeline reduced mouth dryness and increased salivary flow in patients with xerostomia complicating chronic graft-versus-host disease. Biol Blood Marrow Transplant 12(7):792–794Carpenter PA, Schubert MM, Flowers ME. Cevimeline reduced mouth dryness ...
Carpenter PA, Schubert MM, Flowers ME (2006) Cevimeline reduced mouth dryness and increased salivary flow in patients with xerostomia complicating chronic graft-versus-host disease. Biol Blood Marrow Transplant 12(7):792–794Carpenter PA, Schubert MM, Flowers ME. Cevimeline reduced mouth dryness ...